Evidence map›Paper›PMID 26510005›Full record

ArticleAnalytical chemistry2015

Characterization of Traveling Wave Ion Mobility Separations in Structures for Lossless Ion Manipulations.

Ahmed M Hamid, Yehia M Ibrahim, Sandilya V B Garimella, Ian K Webb, Liulin Deng, Tsung-Chi Chen, Gordon A Anderson, Spencer A Prost, Randolph V Norheim, Aleksey V Tolmachev and 1 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
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  15. SLIM Tricks: Tools, Concepts, and Strategies for the Development of Planar Ion Guides.Journal of the American Society for Mass Spectrometry · 2023
    Article
  16. Article
  17. Enhancing the Depth of Analyses with Next-Generation Ion Mobility Experiments.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023
    Review
  18. Identification of Mobility-ResolvedAnalytical chemistry · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmed M HamidBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Yehia M IbrahimBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Sandilya V B GarimellaBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Ian K WebbBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Liulin DengBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Tsung-Chi ChenBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Gordon A AndersonBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Spencer A ProstBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Randolph V NorheimBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Aleksey V TolmachevBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.
Richard D SmithBiological Sciences Division, Pacific Northwest National Laboratory , Richland, Washington 99352, United States.

Funding

Equipment Supplement Request for a Research Resource for Ultra-sensitive High Throughput ProteomicsP41GM103493 · NIGMS · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI SMITH, RICHARD D · 2012 to 2022
$22.6M
NIGMS NIH HHS P41 GM103493
6 · The paper itself

Abstract

We report on the development and characterization of a traveling wave (TW)-based Structures for Lossless Ion Manipulations (TW-SLIM) module for ion mobility separations (IMS). The TW-SLIM module uses parallel arrays of rf electrodes on two closely spaced surfaces for ion confinement, where the rf electrodes are separated by arrays of short electrodes, and using these TWs can be created to drive ion motion. In this initial work, TWs are created by the dynamic application of dc potentials. The capabilities of the TW-SLIM module for efficient ion confinement, lossless ion transport, and ion mobility separations at different rf and TW parameters are reported. The TW-SLIM module is shown to transmit a wide mass range of ions (m/z 200-2500) utilizing a confining rf waveform (∼1 MHz and ∼300 Vp-p) and low TW amplitudes (<20 V). Additionally, the short TW-SLIM module achieved resolutions comparable to existing commercially available low pressure IMS platforms and an ion mobility peak capacity of ∼32 for TW speeds of <210 m/s. TW-SLIM performance was characterized over a wide range of rf and TW parameters and demonstrated robust performance. The combined attributes of the flexible design and low voltage requirements for the TW-SLIM module provide a basis for devices capable of much higher resolution and more complex ion manipulations.

Indexed as

ElectrodesIonsRadio WavesSurface PropertiesIons

Identifiers

PMID26510005
PMCPMC4748841

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.