Evidence map›Paper›PMID 26509860›Full record

ReviewCurrent opinion in supportive and palliative care2015

The last days of life: symptom burden and impact on nutrition and hydration in cancer patients.

David Hui, Rony Dev, Eduardo Bruera

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in supportive and palliative care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Medically assisted hydration for adults receiving palliative care.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
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  7. Article
  8. Observational
  9. Review
  10. Healthcare Professionals' Knowledge, Attitudes and Practices Toward Providing Artificial Nutrition and Hydration for Patients With Terminal Cancer.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article
  11. Article
  12. Article
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  14. Cancer cachexia: A scoping review on non-pharmacological interventions.Asia-Pacific journal of oncology nursing · 2024
    Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David HuiDepartment of Palliative Care and Rehabilitation Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Rony Dev
Eduardo Bruera
The University of Texas MD Anderson Cancer Center · US

Funding

Adjuvant Lorazepam for Agitated Delirium in the Palliative Care UnitR21CA186000 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HUI, DAVID · 2015 to 2016
$399k
NCI NIH HHS R21 CA186000NCI NIH HHS R21CA186000-01A1
6 · The paper itself

Abstract

purpose of reviewTo examine the symptom burden in cancer patients during the last days of life, its impact on nutrition and hydration, and the role of artificial nutrition and hydration in the final days. RECENT

findingsDuring the last days of life, cancer patients often experience progressive functional decline and worsening symptom burden. Many symptoms such as anorexia-cachexia, dysphagia, and delirium could impair oral intake. These, coupled with refractory cachexia, contribute to persistent weight loss and decreased quality of life. Furthermore, the inability to eat/drink and body image changes can result in emotional distress for patients and caregivers. Clinicians caring for these individuals need to ensure longitudinal communication about goals of care, education about the natural process of dying, optimization of symptom management, and provide appropriate emotional support for patients and caregivers. There is a lack of evidence to support that artificial nutrition and hydration can improve outcomes during the last days of life. Artificial nutrition is not recommended because of its invasive nature, whereas artificial hydration may be considered on a case-by-case basis. SUMMARY: This review highlights the need to conduct further research on symptom burden, nutrition, and hydration during the last days of life.

Indexed as

CachexiaCommunicationDeathFluid TherapyHumansNeoplasmsNutritional StatusNutritional SupportPalliative CarePatient Care PlanningPatient Education as TopicQuality of LifeTerminal Care

Identifiers

PMID26509860
PMCPMC4792116
OpenAlexW2418660309

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.