ArticlePloS one2015
Relation of Childhood Home Environment to Cortical Thickness in Late Adolescence: Specificity of Experience and Timing.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.Psychological bulletin · 2020Pooled it
- Sleep and participation in extracurricular activities moderate associations between low SES and brain structure and functional connectivity.Developmental cognitive neuroscience · 2026Article
- Contextualizing Socioeconomic Status Effects on Adolescent Brain Structure and Cognitive Skills: Evidence From the ABCD Study.Developmental science · 2026Article
- Association Between Urban Upbringing and Cortical Gyrification in Persons with Schizophrenia.Indian journal of psychological medicine · 2025Article
- Environmental contributions to cognitive development: The role of cognitive stimulation.Developmental review : DR · 2024Article
- Association between urban upbringing and functional brain connectivity in schizophrenia.Indian journal of psychiatry · 2024Article
- LearningBrain sciences · 2023Article
- Family income buffers the relationship between childhood adverse experiences and putamen volume.Developmental neurobiology · 2023Article
- Normative range parenting and the developing brain: A scoping review and recommendations for future research.The European journal of neuroscience · 2022Article
- Mothers' Attachment Representations and Children's Brain Structure.Frontiers in human neuroscience · 2022Article
- Neurocognitive basis of deductive reasoning in children varies with parental education.Human brain mapping · 2021Article
- Decomposing complex links between the childhood environment and brain structure in school-aged youth.Developmental cognitive neuroscience · 2021Article
- Socio-economic status, executive functions, and theory of mind ability in adolescents: Relationships with language ability and cortisol.The British journal of developmental psychology · 2021Article
- Parent Language Input Prior to School Forecasts Change in Children's Language-Related Cortical Structures During Mid-Adolescence.Frontiers in human neuroscience · 2021Article
- An ecological approach to understanding the developing brain: Examples linking poverty, parenting, neighborhoods, and the brain.The American psychologist · 2020Article
- A review of associations between parental emotion socialization behaviors and the neural substrates of emotional reactivity and regulation in youth.Developmental psychology · 2020Review
- Exposure to violence and low family income are associated with heightened amygdala responsiveness to threat among adolescents.Developmental cognitive neuroscience · 2019Review
- Modelling resilience in adolescence and adversity: a novel framework to inform research and practice.Translational psychiatry · 2019Review
- The role of the visual association cortex in scaffolding prefrontal cortex development: A novel mechanism linking socioeconomic status and executive function.Developmental cognitive neuroscience · 2019Review
- The Neglect-Enrichment Continuum: Characterizing Variation in Early Caregiving Environments.Developmental review : DR · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
What are the long-term effects of childhood experience on brain development? Research with animals shows that the quality of environmental stimulation and parental nurturance both play important roles in shaping lifelong brain structure and function. Human research has so far been limited to the effects of abnormal experience and pathological development. Using a unique longitudinal dataset of in-home measures of childhood experience at ages 4 and 8 and MRI acquired in late adolescence, we were able to relate normal variation in childhood experience to later life cortical thickness. Environmental stimulation at age 4 predicted cortical thickness in a set of automatically derived regions in temporal and prefrontal cortex. In contrast, age 8 experience was not predictive. Parental nurturance was not predictive at either age. This work reveals an association between childhood experience and later brain structure that is specific relative to aspects of experience, regions of brain, and timing.
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