Evidence map›Paper›PMID 26509587›Full record

ArticleKidney international2016

Assessing the risk of incident hypertension and chronic kidney disease after exposure to shock wave lithotripsy and ureteroscopy.

Michelle R Denburg, Thomas O Jemielita, Gregory E Tasian, Kevin Haynes, Phillip Mucksavage, Justine Shults, Lawrence Copelovitch

Open access · greenAbstract read
In one paragraph

Article in Kidney international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Heliyon · 2023
    Article
  8. Pediatric Nephrolithiasis.Healthcare (Basel, Switzerland) · 2023
    Review
  9. Epidemiology of Kidney Stones.Healthcare (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Percutaneous nephrolithotomy in children.Pediatric surgery international · 2021
    Article
  12. Article
  13. Inflammatory Bowel Diseases Are Associated With an Increased Risk for Chronic Kidney Disease, Which Decreases With Age.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020
    Article
  14. Nephrolithiasis: Approach to Diagnosis and Management.Indian journal of pediatrics · 2020
    Review
  15. Article
  16. Antibiotics and Kidney Stones: Perturbation of the Gut-Kidney Axis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2019
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Michelle R DenburgThe Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: denburgm@email.chop.edu.
Thomas O JemielitaCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Gregory E TasianCenter for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kevin HaynesCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Phillip MucksavagePerelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Justine ShultsThe Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lawrence CopelovitchThe Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Renal &Urologic Biostatistics Training GrantT32DK060455 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SHULTS, JUSTINE · 2003 to 2019
$1.9M
Vitamin D Deficiency in Glomerular DiseaseK23DK093556 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI DENBURG, MICHELLE · 2012 to 2016
$858k
Identifying and Mitigating Risk Factors for Dehydration-Mediated Nephrolithiasis in AdolescentsK23DK106428 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI TASIAN, GREGORY EDWARD · 2015 to 2019
$836k
NCRR NIH HHS UL1 RR024134NIDDK NIH HHS K23 DK093556NIDDK NIH HHS K23DK093556NIDDK NIH HHS K23 DK106428NIDDK NIH HHS T32 DK060455
6 · The paper itself

Abstract

In this study we sought to determine if among individuals with urolithiasis, extracorporeal shock wave lithotripsy (SWL) and ureteroscopy are associated with a higher risk of incident arterial hypertension (HTN) and/or chronic kidney disease (CKD). This was measured in a population-based retrospective study of 11,570 participants with incident urolithiasis and 127,464 without urolithiasis in The Health Improvement Network. Patients with pre-existing HTN and CKD were excluded. The study included 1319 and 919 urolithiasis patients with at least one SWL or URS procedure, respectively. Multivariable Cox regression was used to estimate the hazard ratio for incident CKD stage 3-5 and HTN in separate analyses. Over a median of 3.7 and 4.1 years, 1423 and 595 of urolithiasis participants developed HTN and CKD, respectively. Urolithiasis was associated with a significant hazard ratio each for HTN of 1.42 (95% CI: 1.35, 1.51) and for CKD of 1.82 (1.67, 1.98). SWL was associated with a significant increased risk of HTN 1.34 (1.15, 1.57), while ureteroscopy was not. When further stratified as SWL to the kidney or ureter, only SWL to the kidney was significantly and independently associated with HTN 1.40 (1.19, 1.66). Neither SWL nor ureteroscopy was associated with incident CKD. Since urolithiasis itself was associated with a hazard ratio of 1.42 for HTN, an individual who undergoes SWL to the kidney can be expected to have a significantly increased hazard ratio for HTN of 1.96 (1.67, 2.29) compared with an individual without urolithiasis.

Indexed as

AdultCase-Control StudiesDiabetes MellitusFemaleFollow-Up StudiesGoutHumansHypertensionIncidenceKidney CalculiLithotripsyMaleMiddle AgedProportional Hazards ModelsRenal Insufficiency, ChronicRetrospective Studieschronic kidney diseasehypertensionshock wave lithotripsyureteroscopyurolithiasis

Identifiers

PMID26509587
PMCPMC4911906
OpenAlexW2188123415

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.