ArticlePhysics in medicine and biology2015
MRI properties of a unique hypo-intense layer in degraded articular cartilage.
Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Detecting Collagen Fiber Architecture after Destabilization of the Medial Meniscus Surgery Using High-Resolution Diffusion Tensor Imaging.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Magic angle effect on diffusion tensor imaging in ligament and brain.Magnetic resonance imaging · 2022Article
- Structural differences between immature and mature articular cartilage of rabbits by microscopic MRI and polarized light microscopy.Journal of anatomy · 2022Article
- The interface region between articular cartilage and bone by μMRI and PLM at microscopic resolutions.Microscopy research and technique · 2022Article
- Tractography of Porcine Meniscus Microstructure Using High-Resolution Diffusion Magnetic Resonance Imaging.Frontiers in endocrinology · 2022Article
- Effects of Angular Resolution andCartilage · 2021Article
- Resolution-dependent influences of compressed sensing in quantitative T2 mapping of articular cartilage.NMR in biomedicine · 2020Article
- Characterization complex collagen fiber architecture in knee joint using high-resolution diffusion imaging.Magnetic resonance in medicine · 2020Article
- Magnetic resonance imaging (MRI) studies of knee joint under mechanical loading: Review.Magnetic resonance imaging · 2020Review
- Simultaneous tractography and elastography imaging of the zone-specific structural and mechanical responses in articular cartilage under compressive loading.Biomedical optics express · 2019Article
- Article
- Compressed sensing in quantitative determination of GAG concentration in cartilage by microscopic MRI.Magnetic resonance in medicine · 2018Article
- Magic angle effect plays a major role in both T1rho and T2 relaxation in articular cartilage.Osteoarthritis and cartilage · 2017Article
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3 authors.
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Abstract
To investigate the characteristics of a hypo-intense laminar appearance in articular cartilage under external loading, microscopic magnetic resonance imaging (μMRI) T1, T2 and T1ρ experiments of a total of 15 specimens of healthy and trypsin-degraded cartilage were performed at different soaking solutions (saline and 100 mM phosphate buffered saline (PBS)). T2 and T1ρ images of the healthy tissue in saline showed no load-induced laminar appearance, while a hypo-intense layer was clearly visible in the deep part of the degraded tissue at the magic angle. A significant difference was found between T2 values at 0° and 55° (from 16.5 ± 2.8 ms to 20.2 ± 2.7 ms, p = 0.0005), and at 0° and 90° (16.5 ± 2.8 ms to 21.3 ± 2.6 ms, p < 0.0001) in saline solution. In contrast, this hypo-intense laminar appearance largely disappeared when tissue was soaked in PBS. The visualization of this hypo-intensity appearance in different soaking mediums calls for caution in interpreting the data of relaxation times, chemical exchange and collagen fiber deformation.
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