ArticlePloS one2015
Vitamin D Status at Birth and Future Risk of Attention Deficit/Hyperactivity Disorder (ADHD).
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The impact of maternal vitamin D levels during pregnancy and risk of autism spectrum disorder and attention deficit hyperactivity disorder diagnosis and symptoms in offspring: a systematic review and dose-response meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Maternal Vitamin D Levels during Pregnancy and Offspring Psychiatric Outcomes: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Neurodevelopmental effects of prenatal vitamin D in humans: systematic review and meta-analysis.Molecular psychiatry · 2020Pooled it
- Vitamin D Status and Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2018Pooled it
- Circulating levels of maternal vitamin D and risk of ADHD in offspring: results from the Vitamin D Antenatal Asthma Reduction Trial.International journal of epidemiology · 2022Trial
- Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder.World journal of pediatrics : WJP · 2019Trial
- Maternal serum concentrations of vitamin D in pregnancy and preterm birth: a case-control study in Southern Sweden.European journal of nutrition · 2025Article
- The Relationship Between Vitamin D and the Development and Treatment of Attention-Deficit Hyperactivity Disorder: An Overview of Systematic Reviews.Current behavioral neuroscience reports · 2024Article
- Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels.Children (Basel, Switzerland) · 2024Article
- Maternal serum vitamin D level in early pregnancy and risk for preeclampsia: A case-control study in Southern Sweden.PloS one · 2023Article
- Chlorpyrifos residue level and ADHD among children aged 1-6 years in rural China: A cross-sectional study.Frontiers in pediatrics · 2022Article
- Maternal Vitamin D Levels and the Risk of Offspring Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Article
- Gut instincts: vitamin D/vitamin D receptor and microbiome in neurodevelopment disorders.Open biology · 2020Review
- Fetal Programming of Semen Quality (FEPOS) Cohort - A DNBC Male-Offspring Cohort.Clinical epidemiology · 2020Article
- Vitamin D status in children and adults in Sweden: dietary intake and 25-hydroxyvitamin D concentrations in children aged 10-12 years and adults aged 18-80 years.Journal of nutritional science · 2020Article
- Maternal circulating Vitamin DScientific reports · 2019Article
- Significant Effects of Maternal Diet During Pregnancy on the Murine Fetal Brain Transcriptome and Offspring Behavior.Frontiers in neuroscience · 2019Article
- Child Health: Is It Really Assisted Reproductive Technology that We Need to Be Concerned About?Seminars in reproductive medicine · 2018Review
- Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder.Neuropsychiatric disease and treatment · 2018Article
- High maternal vitamin D levels in early pregnancy may protect against behavioral difficulties at preschool age: the Rhea mother-child cohort, Crete, Greece.European child & adolescent psychiatry · 2018Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether children with Attention Deficit/Hyperactivity Disorder have lower levels of Vitamin D3 at birth than matched controls. MATERIAL: Umbilical cord blood samples collected at birth from 202 children later diagnosed with Attention Deficit/Hyperactivity Disorder were analysed for vitamin D content and compared with 202 matched controls. 25-OH vitamin D3 was analysed by liquid chromatography tandem mass spectrometry.
resultsNo differences in cord blood vitamin D concentration were found between children with Attention Deficit/Hyperactivity Disorder (median 13.0 ng/ml) and controls (median 13.5 ng/ml) (p = 0.43). In a logistic regression analysis, Attention Deficit/Hyperactivity Disorder showed a significant association with maternal age (odds ratio: 0.96, 95% confidence interval: 0.92-0.99) but not with vitamin D levels (odds ratio: 0.99, 95% confidence interval: 0.97-1.02).
conclusionWe found no difference in intrauterine vitamin D levels between children later developing Attention Deficit/Hyperactivity Disorder and matched control children. However, the statistical power of the study was too weak to detect an eventual small to medium size association between vitamin D levels and Attention Deficit/Hyperactivity Disorder.
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