Evidence map›Paper›PMID 26509110›Full record

ArticleCurrent stem cell reports2015

Transcriptional Control of Stem and Progenitor Potential.

David E Muench, H Leighton Grimes

Open access · bronzeAbstract read
In one paragraph

Article in Current stem cell reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David E MuenchDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
H Leighton GrimesDivision of Immunobiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Cincinnati Children's Hospital Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
MicroRNA in Acute Myeloid LeukemiaR01CA159845 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI GRIMES, H. LEIGHTON · 2011 to 2015
$1.6M
Developing Novel STAT5 Protein Inhibitors for treatment of leukemiasR21CA186945 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI GRIMES, H. LEIGHTON · 2014 to 2015
$332k
NCATS NIH HHS UL1 TR001425NCI NIH HHS R01 CA159845NCI NIH HHS R21 CA186945
6 · The paper itself

Abstract

Hematopoiesis is characterized by a lifelong balance between hematopoietic stem cell (HSC) self-renewal and differentiation into mature blood populations. Proper instruction of cell fate decisions requires tight homeostatic regulation of transcriptional programs through a combination of epigenetic modifications, management of

Indexed as

Circadian clockEnhancerEpigeneticsHematopoietic stem cellLncRNAsTranscription

Identifiers

PMID26509110
PMCPMC4617301
OpenAlexW2114519604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.