Evidence map›Paper›PMID 26509105›Full record

ArticleCurrent ophthalmology reports2015

Engineering of Human Corneal Endothelial Grafts.

Ying-Ting Zhu, Sean Tighe, Shuang-Ling Chen, Thomas John, Winston Y Kao, Scheffer C G Tseng

Open access · greenAbstract read
In one paragraph

Article in Current ophthalmology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 0 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Human Trabecular Meshwork Progenitors.International journal of medical sciences · 2019
    Review
  8. Review
  9. Human Corneal Endothelial Cells ExpandedInternational journal of medical sciences · 2017
    Review
  10. Senescence Mediated by p16Scientific reports · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ying-Ting ZhuR&D Department, Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, 7000 SW 97 Ave #212, Miami, FL, 33173, USA.
Sean TigheR&D Department, Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, 7000 SW 97 Ave #212, Miami, FL, 33173, USA.
Shuang-Ling ChenR&D Department, Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, 7000 SW 97 Ave #212, Miami, FL, 33173, USA.
Thomas JohnDepartment of Ophthalmology, Loyola University at Chicago, 2160 1 Ave, Maywood, IL 60153, USA.
Winston Y KaoDepartment of Ophthalmology, University of Cincinnati, 2600 Clifton Ave, Cincinnati, OH, 45220, USA.
Scheffer C G TsengR&D Department, Tissue Tech, Inc., Ocular Surface Center, and Ocular Surface Research & Education Foundation, 7000 SW 97 Ave #212, Miami, FL 33173, USA, Telephone: (305) 274-1299.
Ocular Surface Center · USLoyola University Chicago · USUniversity of Cincinnati · US

Funding

Engineering of Human Corneal Endothelial GraftsR44EY022502 · NEI · TISSUETECH, INC. · PI ZHU, YING TING · 2014 to 2015
$1.2M
Engineering of Human Corneal Endothelial GraftsR43EY022502 · NEI · TISSUETECH, INC. · PI ZHU, YING TING · 2012 to 2012
$211k
NEI NIH HHS R43 EY022502NEI NIH HHS R44 EY022502
6 · The paper itself

Abstract

Human corneal endothelial cells (HCEC) play a pivotal role in maintaining corneal transparency. Unlike in other species, HCEC are notorious for their limited proliferative capacity

Indexed as

CorneaCorneal Transparencyendothelial-mesenchymal transition (EMT)human corneal endothelial cells (HCEC)Vision Restoration

Identifiers

PMID26509105
PMCPMC4617200
OpenAlexW1984205522

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.