Evidence map›Paper›PMID 26509055›Full record

ReviewRMD open2015

What makes psoriatic and rheumatoid arthritis so different?

Douglas James Veale, Ursula Fearon

Abstract readReview
In one paragraph

Review in RMD open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Methotrexate for psoriatic arthritis.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Trial
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  5. Review
  6. Article
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Targeted Therapies in Psoriatic Arthritis-An Update.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Douglas James VealeThe Centre for Arthritis and Rheumatic Diseases, EULAR Centre of Excellence, St Vincent's University Hospital, Dublin Academic Medical Centre , Dublin , Ireland ; The Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland.
Ursula FearonThe Centre for Arthritis and Rheumatic Diseases, EULAR Centre of Excellence, St Vincent's University Hospital, Dublin Academic Medical Centre , Dublin , Ireland ; The Conway Institute of Biomolecular and Biomedical Research, University College Dublin , Dublin , Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In many ways, it may be easier to highlight what rheumatoid arthritis (RA) and psoriatic arthritis (PsA) have in common. They are both common conditions characterised by a spectrum of features or clinical manifestations in different organ systems that have led many to conclude that they are actually 'disease syndromes'. Furthermore, many of the organ systems that are affected in both conditions are the same: skin, joints, eyes, vasculature and even the immune system. Indeed, some clinicians fail to recognise these two common arthritides as distinct. And yet, while the manifestations may have a superficial similarity, there are significant differences at a number of levels including clinical, anatomical, microscopic and molecular levels. However, these differences may explain certain clinical manifestations of the two diseases, and more importantly, they may explain different responses to specific therapies and potentially different disease outcomes and prognoses. This may be especially relevant as new therapeutic targets are examined that may be specific for RA or PsA.

Indexed as

DMARDs (biologic)Psoriatic ArthritisRheumatoid ArthritisSynovitis

Identifiers

PMID26509055
PMCPMC4613157

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.