ArticleNeuropsychiatric disease and treatment2015
Increased mean platelet volume in patients with panic disorder.
Article in Neuropsychiatric disease and treatment, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Meta-analysis of peripheral mean platelet volume in patients with mental disorders: Comparisons in depression, anxiety, bipolar disorder, and schizophrenia.Brain and behavior · 2023Pooled it
- Diagnostic value of mean platelet volume for neonatal sepsis: A systematic review and meta-analysis.Medicine · 2020Pooled it
- Depression and Anxiety Symptoms Are Associated with Mean Platelet Volume in Autoimmune Disorders.International journal of environmental research and public health · 2022Article
- Platelet Parameters, C-Reactive Protein, and Depression: An Association Study.International journal of general medicine · 2022Article
- Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder.Molecular psychiatry · 2020Article
- Beyond Haemostasis and Thrombosis: Platelets in Depression and Its Co-Morbidities.International journal of molecular sciences · 2020Review
- Changes in mean platelet volume and hematologic indices in patients with panic disorder due to oxidative stress.Brain and behavior · 2020Article
- Platelet and Red Blood Cell Indices in Patients with Panic Disorder: A Receiver Operating Characteristic Analysis.Journal of neurosciences in rural practice · 2020Article
- Toward a personalized therapy for panic disorder: preliminary considerations from a work in progress.Neuropsychiatric disease and treatment · 2019Review
- The association between mean platelet volume levels and poststroke depression.Brain and behavior · 2018Article
- Anxiety Disorders and Cardiovascular Disease.Current psychiatry reports · 2016Review
- Mean platelet volume and red cell distribution width levels in initial evaluation of panic disorder.Neuropsychiatric disease and treatment · 2016Article
- Mean Platelet Volume and Platelet Distribution Width Level in Patients with Panic Disorder.Journal of neurosciences in rural practiceArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe relationship between platelet activation and psychiatric disorders has been shown in previous work. Mean platelet volume (MPV) is a measure of platelet size and a good indicator of platelet activity, which increases in cardiovascular diseases (CVDs). It is known that anxiety is a considerable factor in the etiology of mortality in CVDs. The aim of the present study was to investigate any probable difference in the MPV of patients with panic disorder (PD).
methodsSixty-one drug-free patients, aged 18-65 years and diagnosed with PD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, were included in the study, along with 63 healthy age- and sex-matched volunteers. The body mass index (BMI) was calculated and MPV measured for each subject.
resultsThe MPV was found to be higher in the PD group compared to the control group (P=0.004). There were no significant differences between the two groups in terms of platelet count or BMI.
conclusionAlterations in platelet activity may be a reflection of abnormal 5-hydroxytryptamine (5-HT) 1A receptor function in the central nervous system of subjects with a diagnosis of PD. These findings may elucidate the relationship between CVDs and PD. The findings of the present study suggest that MPV is increased in PD patients.
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