ArticleBehavioural neurology2015
Assessment of Hair Aluminum, Lead, and Mercury in a Sample of Autistic Egyptian Children: Environmental Risk Factors of Heavy Metals in Autism.
Article in Behavioural neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03495492 (Dermal Chelation Lowers White Blood Cell Count in Chronic Lymphocytic Leukemia), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dermal Chelation Lowers White Blood Cell Count in Chronic Lymphocytic Leukemia
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Association Between Biological Lead Concentrations and Autism Spectrum Disorder (ASD) in Children: a Systematic Review and Meta-Analysis.Biological trace element research · 2023Pooled it
- Heavy metals and neurodevelopment of children in low and middle-income countries: A systematic review.PloS one · 2022Pooled it
- Review
- Environmental Risk Factors, Toxic Metals, and Essential Elements in Urine Samples of Algerian Children with Severe Autism Spectrum Disorder and Neurotypical Children.Biological trace element research · 2026Article
- Diagnostic Utility of Hair Toxic Metals in Autism Spectrum Disorder: Unlocking Biomarkers Among Egyptian Children.Biological trace element research · 2026Article
- Renal osteodystrophy in Egyptian CKD patients: observations from clinically indicated bone biopsies.BMC nephrology · 2026Article
- Hair levels of mercury, lead, and cadmium and their association with glycemic control in Egyptian children with type 1 diabetes.BMC pediatrics · 2025Article
- Human hair as a diagnostic tool in medicine.Biochemistry and biophysics reports · 2025Review
- Heavy metals exposure and risk factors for autism spectrum disorder (ASD) among school children in Makassar City, Indonesia.Toxicology reports · 2025Article
- Article
- Knowledge of autism among students at a South African Institute of Higher Education.Health SA = SA Gesondheid · 2024Article
- Intercontinental insights into autism spectrum disorder: a synthesis of environmental influences and DNA methylation.Environmental epigenetics · 2024Review
- Genetic etiology of autism spectrum disorder in the African population: a scoping review.Frontiers in genetics · 2024Article
- Mercury and Autism Spectrum Disorder: Exploring the Link through Comprehensive Review and Meta-Analysis.Biomedicines · 2023Review
- Review
- Association between heavy metals exposure (cadmium, lead, arsenic, mercury) and child autistic disorder: a systematic review and meta-analysis.Frontiers in pediatrics · 2023Article
- Metal Profiles in Autism Spectrum Disorders: A Crosstalk between Toxic and Essential Metals.International journal of molecular sciences · 2022Review
- Non-parental caregivers, low maternal education, gastrointestinal problems and high blood lead level: predictors related to the severity of autism spectrum disorder in Northeast China.BMC pediatrics · 2022Article
- Influence of the Aryl Hydrocarbon Receptor Activating Environmental Pollutants on Autism Spectrum Disorder.International journal of molecular sciences · 2021Review
- Associations of Metabolic Genes (International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe etiological factors involved in the etiology of autism remain elusive and controversial, but both genetic and environmental factors have been implicated. The aim of this study was to assess the levels and possible environmental risk factors and sources of exposure to mercury, lead, and aluminum in children with autism spectrum disorder (ASD) as compared to their matched controls.
methodsOne hundred ASD children were studied in comparison to 100 controls. All participants were subjected to clinical evaluation and measurement of mercury, lead, and aluminum through hair analysis which reflects past exposure.
resultsThe mean Levels of mercury, lead, and aluminum in hair of the autistic patients were significantly higher than controls. Mercury, lead, and aluminum levels were positively correlated with maternal fish consumptions, living nearby gasoline stations, and the usage of aluminum pans, respectively.
conclusionLevels of mercury, lead, and aluminum in the hair of autistic children are higher than controls. Environmental exposure to these toxic heavy metals, at key times in development, may play a causal role in autism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.