Evidence map›Paper›PMID 26508303›Full record

ArticleBMC research notes2015

Prevalence and antimicrobial susceptibility patterns of Shigella among acute diarrheal outpatients in Mekelle hospital, Northern Ethiopia.

Atsebaha Gebrekidan, Tsehaye Asmelash Dejene, Getahun Kahsay, Araya Gebreysus Wasihun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  6. Trial
  7. Article
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  12. Age-dependent acquisition of IgG antibodies toFrontiers in immunology · 2024
    Article
  13. Article
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  16. Prevalence and Antimicrobial-Resistant Features ofInterdisciplinary perspectives on infectious diseases · 2023
    Review
  17. Antimicrobial Susceptibility Patterns ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  18. Article
  19. Article
  20. Shigella flexneri: an emerging pathogen.Folia microbiologica · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Atsebaha GebrekidanDepartment of Microbiology and Immunology, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, P.O. Box: 1871, Mekelle, Ethiopia. atseba_mu@yahoo.com.
Tsehaye Asmelash DejeneDepartment of Microbiology and Immunology, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, P.O. Box: 1871, Mekelle, Ethiopia. tsehaye93@gmail.com.
Getahun KahsayDepartment of Microbiology and Immunology, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, P.O. Box: 1871, Mekelle, Ethiopia. getahunkahsay@gamil.com.
Araya Gebreysus WasihunDepartment of Microbiology and Immunology, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, P.O. Box: 1871, Mekelle, Ethiopia. araya13e25@gmail.com.
University of Bahrain · BH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmergence of increased antimicrobial resistance of Shigella species is a global challenge, particularly in developing countries where increased misuse of antimicrobial agents occurs. There is no published data in the study area on the prevalence and antimicrobial susceptibility patterns of Shigella among acute diarrheal patients. This study was therefore, under taken to fill this gap.

methodsUsing cross sectional study method, stool specimens were collected from 216 patients with acute diarrhea at Mekelle Hospital from August to November 2014. Standard bacteriological methods were used to isolate and determine the antimicrobial susceptibility patterns of the isolates, and data were analyzed using SPSS version 20.

resultsOut of the total 216 participants, Shigella was isolated from 15 (6.9 %) of the participants. Ten (66.7 %) of the positive isolates were from children <15 years (p = 0.005). Latrine availability, source of drinking water and hand washing habits before meal were statistically significant with shigellosis (p < 0.05). Isolates of Shigella showed 100, 86.7 and 66.7 % resistance to amoxicillin, amoxicillin and cotrimoxazole respectively. Low levels of resistance were observed for norfloxacin and ciprofloxacin (6.7 % each). Overall, 80 % of the isolates showed multidrug resistance.

conclusionShigella isolates were highly resistant to amoxicillin, amoxicillin and cotrimoxazole. However, ciprofloxacin and norfloxacin were effective. Antibiotic surveillance is needed to prevent further emergence of drug resistant Shigella strains. More has to be done in the availability of latrine, supply of safe drinking water to the community to reduce the disease burden.

Indexed as

OutpatientsAcute DiseaseAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDiarrheaDrug Resistance, Multiple, BacterialDysentery, BacillaryEthiopiaFemaleHospitalsHumansInfant

Identifiers

PMID26508303
PMCPMC4624588
OpenAlexW1841732163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.