ArticleProceedings of the National Academy of Sciences of the United States of America2015
Discovery of the magnetic behavior of hemoglobin: A beginning of bioinorganic chemistry.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
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- Electromagnetic fields regulate iron metabolism: From mechanisms to applications.Journal of advanced research · 2026Review
- The protocol for mesoscopic wide-field optical imaging in mice: from zero to hero.Biology methods & protocols · 2026Review
- Sevoflurane and Desflurane Spin-Decoherence Effect on Fe(III)acetylacetonate Redox Process.Molecules (Basel, Switzerland) · 2025Article
- Description of the Electronic Structure of Oxyhemoglobin Using Fe L-Edge X-ray Absorption Spectroscopy.Journal of the American Chemical Society · 2025Article
- Theoretical evaluation of the biological activity of hydrogen.Medical gas research · 2025Review
- Protoporphyrin IX iron(II) revisited. An overview of the Mössbauer spectroscopic parameters of low-spin porphyrin iron(II) complexes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024Review
- Trapping of a phenoxyl radical at a non-haem high-spin iron(II) centre.Nature chemistry · 2024Article
- Case report: MRI and CT imaging features of a melanocytic tumour affecting a cervical vertebra in an adult dog, and review of differential diagnosis for T1W-hyperintense lesions.Frontiers in veterinary science · 2024Article
- Dynamic MRI of the Mesenchymal Stem Cells Distribution during Intravenous Transplantation in a Rat Model of Ischemic Stroke.Life (Basel, Switzerland) · 2023Article
- Metal-organic frameworks as OChemical science · 2022Review
- A Radiological Assessment of Chronic Subdural Hematomas.Korean journal of neurotrauma · 2022Review
- Hypoxia Imaging As a Guide for Hypoxia-Modulated and Hypoxia-Activated Therapy.Antioxidants & redox signaling · 2022Review
- Helminth Eggs as a Magnetic Biomaterial: Introducing a Recognition Probe.Frontiers in veterinary science · 2022Article
- The Oxygen Transport Triad in High-Altitude Pulmonary Edema: A Perspective from the High Andes.International journal of environmental research and public health · 2021Article
- Paramagnetic Shifts and Guest Exchange Kinetics in CoInorganic chemistry · 2020Article
- Magnetic mechanism for the biological functioning of hemoglobin.Scientific reports · 2020Article
- Oxidation of an indole substrate by porphyrin iron(iii) superoxide: relevance to indoleamine and tryptophan 2,3-dioxygenases.Chemical communications (Cambridge, England) · 2020Article
- Leading RNA Interference Therapeutics Part 2: Silencing Delta-Aminolevulinic Acid Synthase 1, with a Focus on Givosiran.Molecular diagnosis & therapy · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Two articles published by Pauling and Coryell in PNAS nearly 80 years ago described in detail the magnetic properties of oxy- and deoxyhemoglobin, as well as those of closely related compounds containing hemes. Their measurements revealed a large difference in magnetism between oxygenated and deoxygenated forms of the protein and, along with consideration of the observed diamagnetism of the carbonmonoxy derivative, led to an electronic structural formulation of oxyhemoglobin. The key role of hemoglobin as the main oxygen carrier in mammalian blood had been established earlier, and its allosteric behavior had been described in the 1920s. The Pauling-Coryell articles on hemoglobin represent truly seminal contributions to the field of bioinorganic chemistry because they are the first to make connections between active site electronic structure and the function of a metalloprotein.
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