ArticleExtremophiles : life under extreme conditions2016
Transcriptional regulation of dimethyl sulfoxide respiration in a haloarchaeon, Haloferax volcanii.
Article in Extremophiles : life under extreme conditions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Analysis of the external signals driving the transcriptional regulation of the main genes involved in denitrification inFrontiers in microbiology · 2023Article
- Comparative Genomic Insights into the Evolution ofmSystems · 2022Article
- Open Issues for Protein Function Assignment inGenes · 2021Article
- Acid Experimental Evolution of the HaloarchaeonFrontiers in microbiology · 2020Article
- Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase.Frontiers in microbiology · 2020Article
- Anaerobic Growth of Haloarchaeon Haloferax volcanii by Denitrification Is Controlled by the Transcription Regulator NarO.Journal of bacteriology · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The halophilic euryarchaeon Haloferax volcanii can grow anaerobically by DMSO respiration. DMSO reductase was induced by DMSO respiration not only under anaerobic growth conditions but also in denitrifying cells of H. volcanii. Deletion of the dmsR gene, encoding a putative regulator for the DMSO reductase, resulted in the loss of anaerobic growth by DMSO respiration. Reporter experiments revealed that only the anaerobic condition was essential for transcription of the dmsEABCD genes encoding DMSO reductase and that transcription was enhanced threefold by supplementation of DMSO. In the ∆dmsR mutant, transcription of the dmsEABCD genes induced by the anaerobic condition was not enhanced by DMSO, suggesting that DmsR is a DMSO-responsive regulator. Transcriptions of the dmsR and mgd genes for Mo-bisMGD biosynthesis were regulated in the same manner as the dmsEABCD genes. These results suggest that the genetic regulation of DMSO respiration in H. volcanii is controlled by at least two systems: one is the DMSO-responsive DmsR, and the other is an unknown anaerobic regulator.
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