ArticleScientific reports2015
Action of multiple intra-QTL genes concerted around a co-localized transcription factor underpins a large effect QTL.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- Transcriptomic Landscape and Regulatory Pathways of Drought Response in Rice (International journal of molecular sciences · 2026Pooled it
- Pooled it
- Physiological and Molecular Characterization of the Drought Tolerance-Related QTL qDTY12.1 in Japonica Rice.Rice (New York, N.Y.) · 2025Article
- Integrated transcriptome and metabolome analysis revealed differential drought stress response mechanisms of wheat seedlings with varying drought tolerance.BMC plant biology · 2025Article
- Extreme trait GWAS (Et-GWAS): Unraveling rare variants in the 3,000 rice genome.Life science alliance · 2024Article
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- Unraveling the genetics underlying micronutrient signatures of diversity panel present in brown rice through genome-ionome linkages.The Plant journal : for cell and molecular biology · 2023Article
- Assessment of Rice Sheath Blight Resistance Including Associations with Plant Architecture, as Revealed by Genome-Wide Association Studies.Rice (New York, N.Y.) · 2022Article
- QTL mapping of drought-related traits in the hybrids of Populus deltoides 'Danhong'×Populus simonii 'Tongliao1'.BMC plant biology · 2022Article
- Genetic mapping reveals complex architecture and candidate genes involved in common bean response to Meloidogyne incognita infection.The plant genome · 2022Article
- DECUSSATE network with flowering genes explains the variable effects of qDTY12.1 to rice yield under drought across genetic backgrounds.The plant genome · 2022Article
- Systems-based rice improvement approaches for sustainable food and nutritional security.Plant cell reports · 2021Review
- A drought-responsive rice amidohydrolase is the elusive plant guanine deaminase with the potential to modulate the epigenome.Physiologia plantarum · 2021Article
- Unraveling regulatory divergence, heterotic malleability, and allelic imbalance switching in rice due to drought stress.Scientific reports · 2021Article
- Molecular Breeding for Improving Productivity ofGenes · 2021Article
- The recombination landscape and multiple QTL mapping in a Solanum tuberosum cv. 'Atlantic'-derived FHeredity · 2021Article
- Comparative Transcriptomics and Co-Expression Networks Reveal Tissue- and Genotype-Specific Responses ofGenes · 2020Article
- Changes in Expression Level ofInternational journal of molecular sciences · 2020Article
- Photosynthesis research: a model to bridge fundamental science, translational products, and socio-economic considerations in agriculture.Journal of experimental botany · 2020Review
Corrections and comments
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Authors and funding
22 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sub-QTLs and multiple intra-QTL genes are hypothesized to underpin large-effect QTLs. Known QTLs over gene families, biosynthetic pathways or certain traits represent functional gene-clusters of genes of the same gene ontology (GO). Gene-clusters containing genes of different GO have not been elaborated, except in silico as coexpressed genes within QTLs. Here we demonstrate the requirement of multiple intra-QTL genes for the full impact of QTL qDTY12.1 on rice yield under drought. Multiple evidences are presented for the need of the transcription factor 'no apical meristem' (OsNAM12.1) and its co-localized target genes of separate GO categories for qDTY12.1 function, raising a regulon-like model of genetic architecture. The molecular underpinnings of qDTY12.1 support its effectiveness in further improving a drought tolerant genotype and for its validity in multiple genotypes/ecosystems/environments. Resolving the combinatorial value of OsNAM12.1 with individual intra-QTL genes notwithstanding, identification and analyses of qDTY12.1has fast-tracked rice improvement towards food security.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.