Evidence map›Paper›PMID 26507497›Full record

ArticleMedizinische Klinik, Intensivmedizin und Notfallmedizin2016

Lung protective ventilation and hospital survival of cardiac intensive care patients.

M Schneck, K Holder, S Gielen, S Nuding, J Schröder, A R Tamm, K Werdan, H Ebelt

Abstract read
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Article in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M SchneckDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany. Michael.Schneck@uk-halle.de.
K HolderDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.
S GielenDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.
S NudingDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.
J SchröderDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.
A R TammDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.
K WerdanDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.
H EbeltDepartment of Medicine III, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097, Halle, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo detect connections between parameters of ventilation and outcomes of cardiac intensive care patients. DESIGN AND

settingNoninterventional study. Between 05/11 and 05/12 all patients with acute heart failure and post cardiopulmonary resuscitation were registered. Lung protective ventilation was defined as peak inspiratory pressure (PIP) < 30 mmHg and tidal volume (Vt) < = 6 ml/kg.

resultsIn total, 129 patients were included in the study, 68.2 % male, age 67.9 ± 13.4 years, weight 71.4 ± 37.2 kg, predictive body weight 66.9 ± 8.8 kg, mortality 47.3 %. Lung protective ventilated patients at day 1: 17.3 % with a significant difference between surviving and nonsurviving patients (24.1 % vs. 9.6 %; p < 0.05). Logistic regression models showed a strong connection between PIP and survival (odds ratio 1.13; p < 0.05). Vt showed no significant influence on survival.

conclusionOur data recommends a strict observance of a low PIP for cardiac intensive care patients, whereas Vt seems to be of secondary importance.

Indexed as

Critical CareRespiration, ArtificialRespiratory Distress SyndromeTidal VolumeAgedFemaleHumansLungMaleMiddle AgedPositive-Pressure RespirationAcute heart failureCardiopulmonary resuscitationLung protectionLung protective ventilationPeak inspiratory pressureTidal volume

Identifiers

PMID26507497

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.