Evidence map›Paper›PMID 26507130›Full record

ReviewCritical care (London, England)2015

Diagnosis and management of inhalation injury: an updated review.

Patrick F Walker, Michelle F Buehner, Leslie A Wood, Nathan L Boyer, Ian R Driscoll, Jonathan B Lundy, Leopoldo C Cancio, Kevin K Chung

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05705713 (First-day Computed Tomography), which is not on this map. Cited by 97 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05705713 nacompletednot on this map

First-day Computed Tomography: Does it Has a Role in the Assessment of Patients With Inhalation Lung Injury?

TypeinterventionalSponsorMenoufia UniversityRan2015 to 2019Enrolled58ConditionsInhalation InjuryArmschest computed tomography (CT)
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Review
  6. Article
  7. Article
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  11. Observational
  12. Association of inhalation injury with ventilator-associated pneumonia and clinical outcomes in critically ill patients with burns: A retrospective study.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2026
    Article
  13. Review
  14. Article
  15. Review
  16. Article
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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patrick F WalkerDepartment of Surgery, Walter Reed National Military Medical Center, 8901 Wisconsin Ave, Bethesda, MD, 20889, USA.
Michelle F BuehnerDepartment of General Surgery, San Antonio Military Medical Center, 3551 Roger Brooke Dr., Fort Sam Houston, TX, 78234, USA. michelle.f.buehner.mil@mail.mil.
Leslie A WoodDepartment of Medicine, San Antonio Military Medical Center, 3551 Roger Brooke Dr., Fort Sam Houston, TX, 78234, USA.
Nathan L BoyerDepartment of Medicine, San Antonio Military Medical Center, 3551 Roger Brooke Dr., Fort Sam Houston, TX, 78234, USA.
Ian R DriscollUnited States Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, USA.
Jonathan B LundyUnited States Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, USA.
Leopoldo C CancioUnited States Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, USA.
Kevin K ChungUnited States Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence. The development of a grading system and the use of modalities such as chest computed tomography may allow for a more nuanced evaluation of inhalation injury and enhanced ability to prognosticate. Supportive respiratory care remains essential in managing inhalation injury. Adjuncts still lacking definitive evidence of efficacy include bronchodilators, mucolytic agents, inhaled anticoagulants, nonconventional ventilator modes, prone positioning, and extracorporeal membrane oxygenation. Recent research focusing on molecular mechanisms involved in inhalation injury has increased the number of potential therapies.

Indexed as

Abbreviated Injury ScaleBronchodilator AgentsBronchoscopyHumansPneumoniaRespiration, ArtificialSmoke Inhalation InjuryBronchodilator Agents

Identifiers

PMID26507130
PMCPMC4624587

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.