ArticleAnnals of Saudi medicine
Prevalence of major congenital anomalies at King Fahad Medical City in Saudi Arabia: a tertiary care centre-based study.
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Birth prevalence of achondroplasia: A systematic literature review and meta-analysis.American journal of medical genetics. Part A · 2020Pooled it
- Assessing signs and impacts of achondroplasia: psychometric evaluation of the Achondroplasia Child Experience Measures.Journal of patient-reported outcomes · 2026Trial
- Maternal Risk Factors, Patterns, and Outcomes of Antenatal Congenital Anomalies: A Hospital-Based Study.Diagnostics (Basel, Switzerland) · 2025Article
- Epidemiology of congenital anomalies in the Gulf Cooperation Council countries: a scoping review.BMJ open · 2025Article
- Live birth prevalence of major congenital anomalies in the United Arab Emirates.Scientific reports · 2025Article
- Public Awareness and Perceptions of Congenital Disabilities in Saudi Arabia: A Cross-Sectional Study.Risk management and healthcare policy · 2025Article
- Analysis of fatal congenital anomalies among pregnant women at Saudi Arabia using ultrasonography.Bioinformation · 2025Article
- Examining the Prevalence of Congenital Anomalies in Newborns: A Cross-Sectional Study at a Tertiary Care Maternity Hospital in Saudi Arabia.Children (Basel, Switzerland) · 2024Article
- Prevalence and Pattern of Birth Defects in Saudi Arabia: A Systematic Review of Observational Studies.Pediatric reports · 2023Review
- Perception of the Saudi Population on Abortion Decisions in Congenital Fetal Anomalies.Cureus · 2022Article
- Identifying multimorbidity patterns of non-communicable diseases in paediatric inpatients: a cross-sectional study in Shanghai, China.BMJ open · 2021Article
- Audit of level II scans in a tertiary center of a middle-income country (MIC).Journal of family medicine and primary care · 2020Article
- Congenital anomalies and associated risk factors in a Saudi population: a cohort study from pregnancy to age 2 years.BMJ open · 2019Article
- Comparison of pregnancy outcomes between women of advanced maternal age (≥35 years) versus younger women in a tertiary care center in Saudi Arabia.Annals of Saudi medicineArticle
- Head and Neck Congenital Anomalies in Neonate Hospitals in Hail, Saudi Arabia.International journal of clinical pediatric dentistryArticle
- Fetal structural anomalies diagnosed during the first, second and third trimesters of pregnancy using ultrasonography: a retrospective cohort study.Sao Paulo medical journal = Revista paulista de medicinaArticle
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe prevalence of major congenital anomalies in Saudi Arabia is a largely understudied area. Knowing the prevalence of birth defects and their trends is important in identifying potential factors that are either causative or preventative. Early antenatal diagnosis of major congenital anomalies is important for possible termination of pregnancy, fetal or neonatal. We determined the prevalence of major congenital anomalies in our hospital population since implementation of an improved screening system. PATIENTS AND
methodsThis single-centre prospective cross-sectional study was conducted in a tertiary care hospital in Riyadh. A total of 63452 obstetrical ultrasound examinations were performed for 30632 female Saudi obstetric patients from the period of January 2007 to December 2012.
resultsA total of 1598 fetuses were diagnosed with major congenital anomalies, including 1064 (66.6 %) fetuses with isolated major anomalies and 534 (33.4%) fetuses with non-isolated major anomalies. The antenatal prevalence of congenital anomalies was 52.1 per 1000 pregnancies. The median maternal age at diagnosis was 29 years. The median gestational age at diagnosis was 30 weeks of gestation. Two hundred and eighty five cases (17.85%) had a previous family history of similar anomalies. The most commonly diagnosed anomalies involved the genitourinary system (652 cases). The birth prevalence of major congenital anomalies was 46.5 per 1000 live births.
conclusionThe prevalence of major congenital anomalies in our hospital population appears to be higher than international prevalences, with a high recurrence rate. Environmental, nutritional and social factors may be contributing to this phenomenon.
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