Evidence map›Paper›PMID 26506844›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017

Cartilage morphology at 2-3 years following anterior cruciate ligament reconstruction with or without concomitant meniscal pathology.

Xinyang Wang, Yuanyuan Wang, Kim L Bennell, Tim V Wrigley, Flavia M Cicuttini, Karine Fortin, David J Saxby, Ans Van Ginckel, Alasdair R Dempsey, Nicole Grigg and 5 more

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Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Bone bruise in anterior cruciate ligament rupture entails a more severe joint damage affecting joint degenerative progression.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xinyang WangCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Yuanyuan WangSchool of Public Health and Preventive Medicine, Alfred Hospital, Monash University, Melbourne, VIC, Australia.
Kim L BennellCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Tim V WrigleyCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Flavia M CicuttiniSchool of Public Health and Preventive Medicine, Alfred Hospital, Monash University, Melbourne, VIC, Australia.
Karine FortinCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.
David J SaxbyCentre for Musculoskeletal Research, Griffith University, The Gold Coast, QLD, Australia.
Ans Van GinckelCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Alasdair R DempseyCentre for Musculoskeletal Research, Griffith University, The Gold Coast, QLD, Australia.
Nicole GriggCentre for Musculoskeletal Research, Griffith University, The Gold Coast, QLD, Australia.
Christopher VertulloOrthopaedic Surgery and Sports Medicine Centre, The Gold Coast, QLD, Australia.
Julian A FellerOrthoSport Victoria, Epworth Richmond, Melbourne, VIC, Australia.
Tim WhiteheadOrthoSport Victoria, Epworth Richmond, Melbourne, VIC, Australia.
David G LloydCentre for Musculoskeletal Research, Griffith University, The Gold Coast, QLD, Australia.
Adam L BryantCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia. albryant@unimelb.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine differences in cartilage morphology between young adults 2-3 years post-anterior cruciate ligament reconstruction (ACLR), with or without meniscal pathology, and control participants.

methodsKnee MRI was performed on 130 participants aged 18-40 years (62 with isolated ACLR, 38 with combined ACLR and meniscal pathology, and 30 healthy controls). Cartilage defects, cartilage volume and bone marrow lesions (BMLs) were assessed from MRI using validated methods.

resultsCartilage defects were more prevalent in the isolated ACLR (69 %) and combined group (84 %) than in controls (10 %, P < 0.001). Furthermore, the combined group showed higher prevalence of cartilage defects on medial femoral condyle (OR 4.7, 95 % CI 1.3-16.6) and patella (OR 7.8, 95 % CI 1.5-40.7) than the isolated ACLR group. Cartilage volume was lower in both ACLR groups compared with controls (medial tibia, lateral tibia and patella, P < 0.05), whilst prevalence of BMLs was higher on lateral tibia (P < 0.001), with no significant differences between the two ACLR groups for either measure.

conclusionsCartilage morphology was worse in ACLR patients compared with healthy controls. ACLR patients with associated meniscal pathology have a higher prevalence of cartilage defects than ACLR patients without meniscal pathology. The findings suggest that concomitant meniscal pathology may lead to a greater risk of future OA than isolated ACLR. LEVEL OF EVIDENCE: III.

Indexed as

Anterior Cruciate Ligament ReconstructionAdolescentAdultAnterior Cruciate LigamentAnthropometryCartilage, ArticularCartilage DiseasesFemaleFollow-Up StudiesHumansJoint InstabilityMagnetic Resonance ImagingMalePrevalenceTibial Meniscus InjuriesYoung AdultAnterior cruciate ligament reconstructionCartilageMagnetic resonance imagingMeniscal injuryOsteoarthritis

Identifiers

PMID26506844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.