Evidence map›Paper›PMID 26506371›Full record

ReviewPharmaceutics2015

Transdermal Drug Delivery: Innovative Pharmaceutical Developments Based on Disruption of the Barrier Properties of the stratum corneum.

Ahlam Zaid Alkilani, Maelíosa T C McCrudden, Ryan F Donnelly

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 342 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
342citing papers in PubMed, 2 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

342 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,067 citations in OpenAlex.

  1. Pooled it
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  11. LiposomalInternational journal of molecular sciences · 2026
    Article
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  18. Therapeutic peptides and proteins: Status and developments in drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  19. Article
  20. Review

282 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Ahlam Zaid AlkilaniSchool of Pharmacy, 97 Lisburn Road, Queens University Belfast, Belfast BT9 7BL, Northern Ireland, UK. azaidalkilani01@qub.ac.uk.
Maelíosa T C McCruddenSchool of Pharmacy, 97 Lisburn Road, Queens University Belfast, Belfast BT9 7BL, Northern Ireland, UK. m.mccrudden@qub.ac.uk.
Ryan F DonnellySchool of Pharmacy, 97 Lisburn Road, Queens University Belfast, Belfast BT9 7BL, Northern Ireland, UK. R.Donnelly@qub.ac.uk.
Queen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin offers an accessible and convenient site for the administration of medications. To this end, the field of transdermal drug delivery, aimed at developing safe and efficacious means of delivering medications across the skin, has in the past and continues to garner much time and investment with the continuous advancement of new and innovative approaches. This review details the progress and current status of the transdermal drug delivery field and describes numerous pharmaceutical developments which have been employed to overcome limitations associated with skin delivery systems. Advantages and disadvantages of the various approaches are detailed, commercially marketed products are highlighted and particular attention is paid to the emerging field of microneedle technologies.

Indexed as

drug deliverymechanical and electrical approachesmicroneedlethermal ablationtransdermalultrasoundvelocity based device

Identifiers

PMID26506371
PMCPMC4695828
OpenAlexW2160760798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.