ArticleInternational journal of environmental research and public health2015
Associations between Bisphenol A Exposure and Reproductive Hormones among Female Workers.
Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Endocrine disruption rewards: bisphenol-A-induced reproductive toxicity and the precision ameliorative potential of flavonoids in preclinical studies. A systematic review and meta-analysis.Frontiers in toxicology · 2025Pooled it
- Temporal and geographic variability of bisphenol levels in humans: A systematic review and meta-analysis of international biomonitoring data.Environmental research · 2025Pooled it
- Review
- Associations between pollutants, the regularity of daily sex hormone patterns, and hormone profiles over a complete menstrual cycle.Reproductive toxicology (Elmsford, N.Y.) · 2026Article
- The impact of Bisphenol-A on human reproductive health.Toxicology reports · 2024Review
- Article
- Toxicological Impact of Bisphenol A on Females' Reproductive System: Review Based on Experimental and Epidemiological Studies.Reproductive sciences (Thousand Oaks, Calif.) · 2024Review
- Invisible Hand behind Female Reproductive Disorders: Bisphenols, Recent Evidence and Future Perspectives.Toxics · 2023Review
- The role of endocrine disruptors in female infertility.Molecular biology reports · 2023Review
- Article
- Different types of bisphenols alter ovarian steroidogenesis: Special attention to BPA.Heliyon · 2023Article
- A Case-Control Study on the Effects of Plasticizers Exposure on Male Fertility.International journal of environmental research and public health · 2022Article
- Bisphenol-A and Female Fertility: An Update of Existing Epidemiological Studies.Journal of clinical medicine · 2022Review
- Female Reproductive Health and Exposure to Phthalates and Bisphenol A: A Cross Sectional Study.Toxics · 2021Article
- Bisphenol A and its effects on the systemic organs of children.European journal of pediatrics · 2021Review
- Effects of Bisphenols on RACK1 Expression and Their Immunological Implications in THP-1 Cells.Frontiers in pharmacology · 2021Article
- Environmental toxins and the impact of other endocrine disrupting chemicals in women's reproductive health.JBRA assisted reproduction · 2019Review
- Application of the Draft NIOSH Occupational Exposure Banding Process to Bisphenol A: A case study.Journal of occupational and environmental hygiene · 2019Article
- Bisphenol A Exposure and Sperm ACHE Hydroxymethylation in Men.International journal of environmental research and public health · 2019Article
- The Impact of Bisphenol A on Fertility, Reproductive System, and Development: A Review of the Literature.International journal of endocrinology · 2019Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The associations between Bisphenol-A (BPA) exposure and reproductive hormone levels among women are unclear. A cross-sectional study was conducted among female workers from BPA-exposed and unexposed factories in China. Women's blood samples were collected for assay of follicle-stimulating hormone (FSH), luteinizing hormone (LH), 17β-Estradiol (E2), prolactin (PRL), and progesterone (PROG). Their urine samples were collected for BPA measurement. In the exposed group, time weighted average exposure to BPA for an 8-h shift (TWA8), a measure incorporating historic exposure level, was generated based on personal air sampling. Multiple linear regression analyses were used to examine linear associations between urine BPA concentration and reproductive hormones after controlling for potential confounders. A total of 106 exposed and 250 unexposed female workers were included in this study. A significant positive association between increased urine BPA concentration and higher PRL and PROG levels were observed. Similar associations were observed after the analysis was carried out separately among the exposed and unexposed workers. In addition, a positive association between urine BPA and E2 was observed among exposed workers with borderline significance, while a statistically significant inverse association between urine BPA and FSH was observed among unexposed group. The results suggest that BPA exposure may lead to alterations in female reproductive hormone levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.