ArticlePloS one2015
High Latent TB Infection Rate and Associated Risk Factors in the Eastern China of Low TB Incidence.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Prevalence of latent tuberculosis infection in Asian nations: A systematic review and meta-analysis.Immunity, inflammation and disease · 2024Pooled it
- The Association Between Diabetes Mellitus and the Risk of Latent Tuberculosis Infection: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Comparative agreement between tuberculin skin test and QuantiFERON-TB Gold In-Tube across different levels of exposure in a college-based tuberculosis outbreak.Frontiers in public health · 2026Article
- Machine learning identifies environmental drivers of pulmonary tuberculosis in Xinjiang a typical arid region of China.Scientific reports · 2025Article
- Enhanced screening for tuberculosis infection among immigrants in southern New Brunswick: A cross-sectional pilot study.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025Article
- Epidemiology of latent tuberculosis and associated risk factors in Al-Madinah, Saudi Arabia: A hospital-based cross-sectional study.Journal of Taibah University Medical Sciences · 2025Article
- Knowledge and Prevalence of Latent Tuberculosis Infection: A Feasibility and Pilot Study in a Primary Healthcare Setting in Rural Eastern Cape, South Africa.International journal of environmental research and public health · 2025Article
- Age-period-cohort study of active pulmonary tuberculosis in eastern China: analysis of 15-year surveillance data.BMC public health · 2025Article
- Latent Tuberculosis Infection among Household Contacts of Drug-sensitive Pulmonary Tuberculosis Patients: A Cross-sectional Study from Medan, Indonesia.Acta medica Philippina · 2025Article
- Article
- Tuberculosis screening characteristics amongst freshmen in Changping District, Beijing, China.BMC infectious diseases · 2023Article
- Multiple imputation using chained equations for missing data in survival models: applied to multidrug-resistant tuberculosis and HIV data.Journal of public health in Africa · 2023Article
- Latent Tuberculosis Infection and Associated Risk Factors among People Living with HIV and HIV-Uninfected Individuals in Lithuania.Pathogens (Basel, Switzerland) · 2023Article
- Prevalence of Latent Tuberculosis Infection (LTBI) in Mexican Patients With Rheumatoid Arthritis (RA).Cureus · 2023Article
- Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes.Current topics in microbiology and immunology · 2023Review
- Identification of RNU44 as an Endogenous Reference Gene for Normalizing Cell-Free RNA in Tuberculosis.Open forum infectious diseases · 2022Article
- Possible sex difference in latent tuberculosis infection risk among close tuberculosis contacts.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Observational
- Latent tuberculosis infection in family members in household contact with active tuberculosis patients in Semarang City, Central Java, Indonesia.Journal of public health in Africa · 2022Article
- Screening of latent tuberculosis infection among patients with diabetes mellitus from a high-burden area in Brazil.Frontiers in clinical diabetes and healthcare · 2022Article
- Integrating interferon-gamma release assay testing into provision of tuberculosis preventive therapy is feasible in a tuberculosis high burden resource-limited setting: A mixed methods study.PLOS global public health · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo disclose the associated risk factors for latent tuberculosis infection (LTBI) and the current situation of LTBI in the eastern China.
methodsA cross-sectional study was undertaken to evaluate the LTBI rate and risk factors.
resultsA total of 5305 subjects were finally included, with the IGRA positive rate of 19.98% (1060/5305). The LTBI rates were increasing with age (ORs were in significance from 6.60 to 20.92). Male gender significantly increased the risk of LTBI by 0.52 fold (OR = 1.52). Both smoking and drinking significantly increased the risk of LTBI (OR = 1.83 and OR = 1.67, respectively). Meanwhile, overweight and close contact with tuberculosis were risk factors for LTBI (OR = 1.36 and OR = 2.38, respectively). However, higher level of education and BCG vaccination lowered the risk of LTBI (OR = 0.16 and OR = 0.39, respectively). The multivariate logistic regression showed that age, male gender, smoking, overweight and close contacting with tuberculosis were risk factors for LTBI, but BCG vaccination was a protective factor for LTBI.
conclusionsBCG vaccination exerted protective effect on tuberculosis. However, LTBI rate in the Chinese rural area was critical and subjects above 30 years, male, smoking, overweight and close contact with tuberculosis wound be the targets for LTBI screening and source of tuberculosis.
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