ArticleChemical communications (Cambridge, England)2016
Targeted delivery of gold nanoparticle contrast agents for reporting gene detection by magnetic resonance imaging.
Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Alkaline Phosphatase-Targeted, Gadolinium-Labeled Nanoparticles for Enhanced Multimodal Imaging of Liver Cancer.ACS applied materials & interfaces · 2025Article
- HaloTag-Modified, Ferrocene Labeled Self-Assembled Monolayers for Protein Sensing.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- HaloTag display enables quantitative single-particle characterisation and functionalisation of engineered extracellular vesicles.Journal of extracellular vesicles · 2024Article
- Engineered Nonviral Protein Cages Modified for MR Imaging.ACS applied bio materials · 2023Article
- Molecular Magnetic Resonance Imaging with Gd(III)-Based Contrast Agents: Challenges and Key Advances.Journal of the American Chemical Society · 2019Review
- A Markedly Improved Synthetic Approach for the Preparation of Multifunctional Au-DNA Nanoparticle Conjugates Modified with Optical and MR Imaging Probes.Bioconjugate chemistry · 2018Article
- Cell Penetration Profiling Using the Chloroalkane Penetration Assay.Journal of the American Chemical Society · 2018Article
- Effect of Magnetic Coupling on Water Proton Relaxivity in a Series of Transition Metal GdInorganic chemistry · 2018Article
- Controlled in-cell activation of RNA therapeutics using bond-cleaving bio-orthogonal chemistry.Chemical science · 2017Article
- Second-GenerationGenetics · 2017Article
- Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field.Nano letters · 2016Article
- Click Chemistry in the Development of Contrast Agents for Magnetic Resonance Imaging.Topics in magnetic resonance imaging : TMRI · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Detection of protein expression by MRI requires a high payload of Gd(III) per protein binding event. Presented here is a targeted AuDNA nanoparticle capable of delivering several hundred Gd(III) chelates to the HaloTag reporter protein. Incubating this particle with HaloTag-expressing cells produced a 9.4 contrast-to-noise ratio compared to non-expressing cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.