ArticleBiomedical optics express2015
Validating a bimodal intravascular ultrasound (IVUS) and near-infrared fluorescence (NIRF) catheter for atherosclerotic plaque detection in rabbits.
Article in Biomedical optics express, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 37 citations in OpenAlex.
- High-Speed Intravascular Near-Infrared Fluorescence-Ultrasound Imaging In Vivo.IEEE transactions on bio-medical engineering · 2026Article
- Clinical ultrasound, photoacoustic, and fluorescence image-guided lymphovenous anastomosis microsurgery via a transparent ultrasound transducer array.Nature communications · 2025Article
- Optical theranostics in ischemic heart disease: from molecular insights to clinical translation.Theranostics · 2025Review
- Mechanisms of delayed indocyanine green fluorescence and applications to clinical disease processes.Surgery · 2024Review
- Intravascular ICG-enhanced NIRF-IVUS imaging to assess progressive atherosclerotic lesions in excised human coronary arteries.NPJ cardiovascular health · 2024Article
- Accounting for blood attenuation in intravascular near-infrared fluorescence-ultrasound imaging using a fluorophore-coated guidewire.Journal of biomedical optics · 2023Article
- Imaging Carotid Plaque Burden in Living Mice via Hybrid Semiconducting Polymer Nanoparticles-Based Near-Infrared-II Fluorescence and Magnetic Resonance Imaging.Research (Washington, D.C.) · 2023Article
- Intracoronary Imaging of Vulnerable Plaque-From Clinical Research to Everyday Practice.Journal of clinical medicine · 2022Review
- Intravascular molecular-structural imaging with a miniaturized integrated near-infrared fluorescence and ultrasound catheter.Journal of biophotonics · 2021Article
- Mechanically Rotating Intravascular Ultrasound (IVUS) Transducer: A Review.Sensors (Basel, Switzerland) · 2021Review
- Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging.Sensors (Basel, Switzerland) · 2021Review
- Tumor-Targeting Glycol Chitosan Nanoparticles for Image-Guided Surgery of Rabbit Orthotopic VX2 Lung Cancer.Pharmaceutics · 2020Article
- 3-D-Printed Registration Phantom for Combined Ultrasound and Optical Imaging of Biological Tissues.Ultrasound in medicine & biology · 2020Article
- Platform for quantitative multiscale imaging of tissue composition.Biomedical optics express · 2020Article
- Intravascular Molecular Imaging: Near-Infrared Fluorescence as a New Frontier.Frontiers in cardiovascular medicine · 2020Review
- Multimodal intravascular imaging technology for characterization of atherosclerosis.Journal of innovative optical health sciences · 2020Article
- Cardiovascular optoacoustics: From mice to men - A review.Photoacoustics · 2019Review
- In Vivo Near-Infrared Fluorescence Imaging of Atherosclerosis Using Local Delivery of Novel Targeted Molecular Probes.Scientific reports · 2019Article
- Position Paper Computational Cardiology.IEEE journal of biomedical and health informatics · 2019Article
- Intravascular Optical Coherence Tomography for Characterization of Atherosclerosis with a 1.7 Micron Swept-Source Laser.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary artery disease is characterized by atherosclerotic plaque formation. Despite impressive advances in intravascular imaging modalities, in vivo molecular plaque characterization remains challenging, and different multimodality imaging systems have been proposed. We validated an engineered bimodal intravascular ultrasound imaging (IVUS) / near-infrared fluorescence (NIRF) imaging catheter in vivo using a balloon injury atherosclerosis rabbit model. Rabbit aortas and right iliac arteries were scanned in vivo after indocyanine green (ICG) injection, and compared to corresponding ex vivo fluorescence and white light images. Areas of ICG accumulation were colocalized with macroscopic atherosclerotic plaque formation. In vivo imaging was performed with the bimodal catheter integrating ICG-induced fluorescence signals into cross-sectional IVUS imaging. In vivo ICG accumulation corresponded to ex vivo fluorescence signal intensity and IVUS identified plaques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.