Evidence map›Paper›PMID 26504588›Full record

ArticleBiomaterials research2015

Preparation and investigation of hydrolyzed polyacrylonitrile as a preliminary biomedical hydrogel.

Ji Hoon Park, Guo Zhe Tai, Bo Keun Lee, Seung Hun Park, Ja Yong Jang, Jung Soo Lee, Jae Ho Kim, Kwideok Park, Ju Woong Jang, Moon Suk Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ji Hoon ParkDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.
Guo Zhe TaiDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.
Bo Keun LeeDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.
Seung Hun ParkDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.
Ja Yong JangDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.
Jung Soo LeeDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea ; R&DB Center, Cellumed Co., Ltd., Seoul, 153-803 South Korea.
Jae Ho KimDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.
Kwideok ParkCenter for Biomaterials, Korea Institute of Science and Technology, Seoul, 136-791 South Korea.
Ju Woong JangR&DB Center, Cellumed Co., Ltd., Seoul, 153-803 South Korea.
Moon Suk KimDepartment of Molecular Science and Technology, Ajou University, Suwon, 443-759 South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHydrolyzed polyacrylonitrile (HPAN) has attracted much attention as a hydrogel for a broad range of biomedical applications. Therefore, in this study, we prepared HPAN derivatives with controllable compositions by the radical polymerization of acrylonitrile (AN), methacrylic acid (MAA) and N-isopropylacrylamide (NIPAM) monomers.

resultsThe prepared poly(AN-co-MAA-co-NIPAM) copolymers had different ratios of AN, MAA, and NIPAM and molecular weights ranging from 2000 to 50,000. The copolymers were prepared as films to examine their properties. The prepared copolymer films showed different solubilities, contact angles, and swelling ratios. The properties of the copolymer films were affected by the hydrophobic PAN segments and the hydrophilic PMAA or PNIPAM segments.

conclusionThus, we conclude that introducing PMAA and PNIPAM segments with different ratios and lengths into PAN segments could represent a method of controlling the hydrogel properties of copolymers.

Indexed as

Biomedical applicationsHydrogelHydrolyzed polyacrylonitrileRadical polymerizationSwelling

Identifiers

PMID26504588
PMCPMC4620644

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.