Evidence map›Paper›PMID 26504380›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2015

The effect of dietary antioxidant on the COPD risk: the community-based KoGES (Ansan-Anseong) cohort.

Pankaj Joshi, Woo Jin Kim, Sang-Ah Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pankaj JoshiDepartment of Preventive Medicine, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea ; BIT Medical Convergence Graduate Program, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea.
Woo Jin KimDepartment of Internal Medicine, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea ; Environmental Health Center, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea.
Sang-Ah LeeDepartment of Preventive Medicine, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea ; BIT Medical Convergence Graduate Program, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea ; Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do, South Korea.
Kangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary antioxidants have been suggested to have protective role against chronic obstructive pulmonary disease (COPD), but few prospective studies examined this relationship. The prospective study was conducted to evaluate the effect of dietary antioxidants on COPD risk and lung function in the Korean population.

methodsThe data were collected from the community-based Korean Genome Epidemiology Study (KoGES) cohort. To diagnose COPD, forced expiratory volume (FEV1) and forced vital capacity (FVC) were measured by spirometry. The dietary intake of antioxidant vitamins was estimated from validated Food-Frequency Questionnaire. For the analysis, 325 COPD patients and 6,781 at risk subjects were selected from the cohort of 10,038 subjects. Multiple logistic regression models were used to examine the odds ratio (OR) after adjusting for age, sex, marital status, income, history of asthma, history of tuberculosis, and smoking.

resultsThe risk of COPD was positively associated with aging, low education, low household income, lower body mass index, and cigarette smoking. The risk of COPD decreased with increase in the dietary vitamin C (ORQ1 vs Q5=0.66, P trend=0.03) and vitamin E (ORQ1 vs Q5=0.56, P trend=0.05) intake, predominantly, in men (P trend=0.01 and 0.05 for vitamins C and E, respectively). In addition, the lung function was significantly improved with increase in vitamins C (FEV1, P=0.04; FVC, P=0.03) and E (FEV1, P=0.03; FVC, P=0.04) intake. No statistically significant interactions were observed between smoking and vitamin C or E intake in relation to COPD risk among men.

conclusionOur results suggest the independent beneficial effect of antioxidants, particularly vitamins C and E, on COPD risk and lung function in men.

Indexed as

Feeding BehaviorPulmonary Disease, Chronic ObstructiveAdultAgedAntioxidantsFemaleHumansMaleMiddle AgedProtective FactorsRepublic of KoreaRespiratory Function TestsRisk FactorsRisk Reduction BehaviorSocioeconomic FactorsSurveys and QuestionnairesAntioxidantsVitaminsantioxidant vitamins intakechronic obstructive pulmonary disease (COPD)lung functionsmokingthe combined effect of smoking and antioxidant vitamins

Identifiers

PMID26504380
PMCPMC4603710
OpenAlexW1957649732

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.