ArticleTrends in developmental biology
Evolution, structure, and synthesis of vertebrate egg-coat proteins.
Article in Trends in developmental biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 40 citations in OpenAlex.
- Co-Option and Conflict: The Deep Evolutionary History of ZP-Domain Proteins from ECMs to Species Barriers.International journal of molecular sciences · 2026Review
- Growth period of Kinosternon scorpioides changes the ovary morphology by follicular differentiation and structural reorganization.Scientific reports · 2025Article
- Crossing the barrier or how regulation of ovastacin controls fertilization and translates into clinical phenotypes.iScience · 2025Review
- Convergent Evolutionary Dead-End and Breakdown of Hard Chorion in Parental-Egg-Care Fish Reproductive Strategies.Molecular ecology · 2025Article
- Female fertility and the mammalian egg'sHistology and histopathology · 2024Review
- Single-cell RNA sequencing of human oocytes reveals a differential transcriptomic profile associated with agar-like zona pellucida.Journal of ovarian research · 2024Article
- A heterozygousiScience · 2023Article
- A Quantitative Histologic Analysis of Oogenesis in the Flatfish SpeciesAnimals : an open access journal from MDPI · 2023Article
- Article
- MYO10 promotes transzonal projection-dependent germ line-somatic contact during mammalian folliculogenesis†.Biology of reproduction · 2022Article
- Identification of Sperm-Binding Sites in the N-Terminal Domain of Bovine Egg Coat Glycoprotein ZP4.International journal of molecular sciences · 2022Article
- Transcriptome and Proteome Analysis Revealed Key Pathways Regulating Final Stage of Oocyte Maturation of the Turkey (International journal of molecular sciences · 2021Article
- Zona Pellucida Genes and Proteins: Essential Players in Mammalian Oogenesis and Fertility.Genes · 2021Review
- Article
- Review
- Proteomics support the threespine stickleback egg coat as a protective oocyte envelope.Molecular reproduction and development · 2021Article
- Review
- Mammalian egg coat modifications and the block to polyspermy.Molecular reproduction and development · 2020Review
- Zona pellucida genes and proteins and human fertility.Trends in developmental biology · 2020Article
- Exploration of tissue-specific gene expression patterns underlying timing of breeding in contrasting temperature environments in a song bird.BMC genomics · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
All vertebrate eggs are surrounded by an extracellular coat that supports growth of oocytes, protects oocytes, eggs, and early embryos, and participates in the process of fertilization. In mammals (platypus to human beings) the coat is called a zona pellucida (ZP) and in non-mammals (molluscs to birds), a vitelline envelope (VE). The ZP and VE are composed of just a few proteins that are related to one another and possess a common motif, called the zona pellucida domain (ZPD). The ZPD arose more than ~600 million years ago, consists of ~260 amino acids, and has 8 conserved Cys residues that participate in 4 intramolecular disulfides. It is likely that egg-coat proteins are derived from a common ancestral gene. This gene duplicated several times during evolution and gave rise to 3-4 genes in fish, 5 genes in amphibians, 6 genes in birds, and 3-4 genes in mammals. Some highly divergent sequences, N- and C-terminal to the ZPD, have been identified in egg-coat proteins and some of these sequences may be under positive Darwinian selection that drives evolution of the proteins. These and other aspects of egg-coat proteins, including their structure and synthesis, are addressed in this review.
Indexed as
Identifiers
26504367PMC4618670W2412155687What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.