Evidence map›Paper›PMID 26503895›Full record

ArticleRetinal physician2015

Emerging Treatments for Retinitis Pigmentosa: Genes and stem cells, as well as new electronic and medical therapies, are gaining ground.

Michael K Lin, Yi-Ting Tsai, Stephen H Tsang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Retinal physician, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Translation of CRISPR Genome Surgery to the Bedside for Retinal Diseases.Frontiers in cell and developmental biology · 2018
    Review
  8. Review
  9. Genome Surgery and Gene Therapy in Retinal Disorders.The Yale journal of biology and medicine · 2017
    Review
  10. Structural modeling of a novelMolecular genetics & genomic medicine · 2017
    Article
  11. Review
  12. Gene and cell-based therapies for inherited retinal disorders: An update.American journal of medical genetics. Part C, Seminars in medical genetics · 2016
    Review
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael K LinMichael K. Lin, ScB, is a research fellow in the Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Stem Cell and Regenerative Medicine Laboratory in the Edward S. Harkness Eye Institute and a medical student in the College of Physicians and Surgeons at Columbia University in New York. Yi-Ting Tsai, MS, is a doctoral student in the Institute of Human Nutrition at Columbia University in New York Stephen H. Tsang, MD, PhD, is an ophthalmic geneticist and electroretinography (ERG) attending at New York Presbyterian Hospital.
Yi-Ting TsaiMichael K. Lin, ScB, is a research fellow in the Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Stem Cell and Regenerative Medicine Laboratory in the Edward S. Harkness Eye Institute and a medical student in the College of Physicians and Surgeons at Columbia University in New York. Yi-Ting Tsai, MS, is a doctoral student in the Institute of Human Nutrition at Columbia University in New York Stephen H. Tsang, MD, PhD, is an ophthalmic geneticist and electroretinography (ERG) attending at New York Presbyterian Hospital.
Stephen H TsangMichael K. Lin, ScB, is a research fellow in the Bernard and Shirlee Brown Glaucoma Laboratory and Barbara & Donald Jonas Stem Cell and Regenerative Medicine Laboratory in the Edward S. Harkness Eye Institute and a medical student in the College of Physicians and Surgeons at Columbia University in New York. Yi-Ting Tsai, MS, is a doctoral student in the Institute of Human Nutrition at Columbia University in New York Stephen H. Tsang, MD, PhD, is an ophthalmic geneticist and electroretinography (ERG) attending at New York Presbyterian Hospital.
Regenerative Medicine Institute · MX

Funding

Toward mechanism- and gene-based therapies for retinal degenerationR01EY018213 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Stephen H Tsang · 2008 to 2026
$6.6M
Evaluating GWAS AMD Candidate Loci by Gene Editing in Human iPS CellsR21AG050437 · NIA · UNIVERSITY OF IOWA · PI BASSUK, ALEXANDER G, MAHAJAN, VINIT B · 2015 to 2016
$431k
NEI NIH HHS R01 EY018213NIA NIH HHS R21 AG050437
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID26503895
PMCPMC4617761
OpenAlexW1839670460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.