ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2016
Associations of Computed Tomography-Based Trunk Muscle Size and Density With Balance and Falls in Older Adults.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- Effect of exercise modality and weight loss on changes in muscle and bone quality in older adults with obesity.Experimental gerontology · 2023Trial
- Vitamin D supplements for trunk muscle morphology in older adults: secondary analysis of a randomized controlled trial.Journal of cachexia, sarcopenia and muscle · 2019Trial
- The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV.The Journal of frailty & aging · 2019Trial
- Antiretroviral initiation is associated with increased skeletal muscle area and fat content.AIDS (London, England) · 2017Trial
- Observational
- Association of immune checkpoint inhibitors with muscle mass and density in patients with melanoma.The oncologist · 2026Article
- Association of computed tomography (CT)-derived muscle area and density at multiple sites with 10-year fracture risk in older men.JBMR plus · 2026Article
- Associations Between Deep Learning-Derived Fat, Muscle, and Bone Measures From Abdominal Computed Tomography Scans and Fall Risk in Persons Aged 20 Years or Older.Mayo Clinic proceedings. Digital health · 2025Article
- Evaluation of Trunk Muscle Mass in Older Adults Using Bioelectrical Impedance Analysis: A Scoping Review.JMA journal · 2025Review
- Development of a deep learning model for predicting skeletal muscle density from ultrasound data: a proof-of-concept study.La Radiologia medica · 2025Article
- The role of proximal femoral bone, muscle and subcutaneous adipose tissue in the discriminating of hip fracture types in elderly women.BMC musculoskeletal disorders · 2025Article
- Article
- Review
- Optimal lumbar vertebral level for trunk muscle CT assessments in opportunistic sarcopenia screening: a cross-sectional study.BMJ open · 2025Article
- Variations of QCT-based abdominal and paravertebral muscle tissue content by age and gender.BMC musculoskeletal disorders · 2025Article
- Preoperative myosteatosis and perioperative serum chloride levels predict 180 day major complications after radical cystectomy.Scientific reports · 2025Article
- Sarcopenia, Depressive Symptoms, and Fall Risk: Insights from a National Cohort Study in the Chinese Population.Risk management and healthcare policy · 2025Article
- Age-related changes in ultrasound-assessed muscle composition and postural stability.Scientific reports · 2024Article
- Relationship between muscle and subcutaneous adipose tissue size and density and proximal femur bone in elderly women with hip fracture.Aging clinical and experimental research · 2024Article
- Muscle density, but not size, is independently associated with cognitive health in older adults with hip fractures.JBMR plus · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundDeficits in balance and muscle function are important risk factors for falls in older adults. Aging is associated with significant declines in muscle size and density, but associations of trunk muscle size and density with balance and falls in older adults have not been previously examined.
methodsTrunk muscle size (cross-sectional area) and attenuation (a measure of tissue density) were measured in computed tomography scans (at the L2 lumbar level) in a cohort of older adults (mean ± SD age of 81.9±6.4) residing in independent living communities. Outcome measures were postural sway measured during quiet standing and Short Physical Performance Battery (SPPB) at baseline, and falls reported by participants for up to 3 years after baseline measurements.
resultsHigher muscle density was associated with reduced postural sway, particularly sway velocities, in both men and women, and better Short Physical Performance Battery score in women, but was not associated with falls. Larger muscle size was associated with increased postural sway in men and women and with increased likelihood of falling in men.
conclusionsThe results suggest that balance depends more on muscle quality than on the size of the muscle. The unexpected finding that larger muscle size was associated with increased postural sway and increased fall risk requires further investigation, but highlights the importance of factors besides muscle size in muscle function in older adults.
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