ArticleCerebral cortex (New York, N.Y. : 1991)2017
Electrophysiological Responses in the Ventral Temporal Cortex During Reading of Numerals and Calculation.
Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brain-wide decoding of numbers and letters: Converging evidence from multivariate fMRI analysis and probabilistic meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Pooled it
- Regions in the human inferior temporal gyrus are engaged in numerosity processing across visual stimulus categories.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Temporal order of activations and interactions during arithmetic calculations measured by intracranial electrophysiological recordings in the human brain.Scientific reports · 2026Article
- Crossroads in the Learning Brain: The Neural Overlap Between Arithmetic and Phonological Processing.Human brain mapping · 2026Article
- Spatiotemporal Dynamics of Successive Activations across the Human Brain during Simple Arithmetic Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Investigating the Triple Code Model in numerical cognition using stereotactic electroencephalography.PloS one · 2024Article
- Structural and functional connectivity of the inferior temporal numeral area.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Nonsymbolic Numerosity Maps at the Occipitotemporal Cortex Respond to Symbolic Numbers.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Brains and algorithms partially converge in natural language processing.Communications biology · 2022Article
- Causal dynamics and information flow in parietal-temporal-hippocampal circuits during mental arithmetic revealed by high-temporal resolution human intracranial EEG.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Article
- The impact of musical training in symbolic and non-symbolic audiovisual judgements of magnitude.PloS one · 2022Article
- Electrocorticography Evidence of Tactile Responses in Visual Cortices.Brain topography · 2020Article
- Network topology of symbolic and nonsymbolic number comparison.Network neuroscience (Cambridge, Mass.) · 2020Article
- Mental Shopping Calculations: A Transcranial Magnetic Stimulation Study.Frontiers in psychology · 2020Review
- Separate lanes for adding and reading in the white matter highways of the human brain.Nature communications · 2019Article
- Decoding the processing stages of mental arithmetic with magnetoencephalography.Cortex; a journal devoted to the study of the nervous system and behavior · 2019Article
- Brain Mechanisms of Arithmetic: A Crucial Role for Ventral Temporal Cortex.Journal of cognitive neuroscience · 2018Article
- Neuronal Population Responses in the Human Ventral Temporal and Lateral Parietal Cortex during Arithmetic Processing with Digits and Number Words.Journal of cognitive neuroscience · 2018Article
- A preference for mathematical processing outweighs the selectivity for Arabic numbers in the inferior temporal gyrus.NeuroImage · 2018Article
- Connectivity of the Human Number Form Area Reveals Development of a Cortical Network for Mathematics.Frontiers in human neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Recent evidence suggests that specific neuronal populations in the ventral temporal cortex show larger electrophysiological responses to visual numerals compared with morphologically similar stimuli. This study investigates how these responses change from simple reading of numerals to the active use of numerals in an arithmetic context. We recorded high-frequency broadband (HFB) signals, a reliable measure for local neuronal population activity, while 10 epilepsy patients implanted with subdural electrodes performed separate numeral reading and calculation tasks. We found that calculation increased activity in the posterior inferior temporal gyrus (ITG) with a factor of approximately 1.5 over the first 500 ms of calculation, whereas no such increase was noted for reading numerals without calculation or reading and judging memory statements. In a second experiment conducted in 2 of the same subjects, we show that HFB responses increase in a systematic manner when the single numerals were presented successively in a calculation context: The HFB response in the ITG, to the second and third numerals (i.e., b and c in a + b = c), was approximately 1.5 times larger than the responses to the first numeral (a). These results provide electrophysiological evidence for modulation of local neuronal population responses to visual stimuli based on increasing task demands.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.