SynthesisInfection control and hospital epidemiology2016
Diabetes and Risk of Surgical Site Infection: A Systematic Review and Meta-analysis.
Synthesis in Infection control and hospital epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 246 papers, 13 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Continuous Glycemia Monitoring in Perioperative Period in Patients Undergoing Total Knee or Hip Arthroplasty: a Protocol of Observational Study
Use of Topical Broad-spectrum Antibiotics as a Prophylaxis for Surgical Site Infection
Who cites it
246 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Diabetes is associated with elevated mortality, stroke, and osteoradionecrosis in squamous cell carcinomas of the head and neck: a systematic review and meta-analysis.BMC oral health · 2026Pooled it
- Mechanical and oral antibiotics bowel preparation reduce the risk of surgical site infections and anastomotic leakage in colorectal surgery: a GRADE-based meta-analysis and trial sequential analysis.Frontiers in medicine · 2026Pooled it
- Systematic review of risk prediction models for surgical site infection after abdominal surgery in adults.Frontiers in public health · 2026Pooled it
- Intensive vs. conventional insulin therapy in neurosurgical patients: a meta-analysis of postoperative infections and hypoglycemic risks.Neurosurgical review · 2025Pooled it
- Incidence and Risk Factors of Surgical Site Infection in Abdominal Surgeries: A Scoping Review of Cohort and Case-Control Studies.Iranian journal of medical sciences · 2024Pooled it
- Pooled it
- Predisposing Factors of Nosocomial Infections in Hospitalized Patients in the United Kingdom: Systematic Review.JMIR public health and surveillance · 2023Pooled it
- Risk factors for surgical site infection in patients with gastric cancer: A meta-analysis.International wound journal · 2023Pooled it
- Prevalence of surgical site infections after open reduction and internal fixation for mandibular fractures: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Neuromodulation Interventions for the Treatment of Painful Diabetic Neuropathy: a Systematic Review.Current pain and headache reports · 2022Pooled it
- The impact of preoperative glycated hemoglobin (HbA1c) on postoperative complications after elective major abdominal surgery: a meta-analysis.Korean journal of anesthesiology · 2022Pooled it
- Clinical consequences of head and neck free-flap reconstructions in the DM population.Scientific reports · 2021Pooled it
- The influence of diabetes on postoperative complications following colorectal surgery.Techniques in coloproctology · 2021Pooled it
- Prevention of Infections in Cardiac Surgery (PICS)-Prevena Study - A pilot/vanguard factorial cluster cross-over RCT.PloS one · 2025Trial
- Prevention of postoperative surgical wound complications in ankle and distal tibia fractures: results of Incisional Negative Pressure Wound Therapy.Acta bio-medica : Atenei Parmensis · 2020Trial
- Article
- Economic Impact of Multidisciplinary Pre-operative Diabetes Care Versus Usual Care in Adults Undergoing Elective Non-cardiac Surgery in Australia: A Trial-Based Analysis.Diabetes, obesity & metabolism · 2026Article
- Article
- Post Weight Loss Body Contouring Surgery: Complication Rates Following Bariatric Surgery, Injectable Glucagon-like Peptide-1 Receptor Agonist Pharmacotherapy, Combination Therapy, and Lifestyle Modification.Aesthetic surgery journal · 2026Article
- Review
186 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
OBJECTIVE To determine the independent association between diabetes and surgical site infection (SSI) across multiple surgical procedures. DESIGN Systematic review and meta-analysis. METHODS Studies indexed in PubMed published between December 1985 and through July 2015 were identified through the search terms "risk factors" or "glucose" and "surgical site infection." A total of 3,631 abstracts were identified through the initial search terms. Full texts were reviewed for 522 articles. Of these, 94 articles met the criteria for inclusion. Standardized data collection forms were used to extract study-specific estimates for diabetes, blood glucose levels, and body mass index (BMI). A random-effects meta-analysis was used to generate pooled estimates, and meta-regression was used to evaluate specific hypothesized sources of heterogeneity. RESULTS The primary outcome was SSI, as defined by the Centers for Disease Control and Prevention surveillance criteria. The overall effect size for the association between diabetes and SSI was odds ratio (OR)=1.53 (95% predictive interval [PI], 1.11-2.12; I2, 57.2%). SSI class, study design, or patient BMI did not significantly impact study results in a meta-regression model. The association was higher for cardiac surgery 2.03 (95% PI, 1.13-4.05) compared with surgeries of other types (P=.001). CONCLUSIONS These results support the consideration of diabetes as an independent risk factor for SSIs for multiple surgical procedure types. Continued efforts are needed to improve surgical outcomes for diabetic patients. Infect. Control Hosp. Epidemiol. 2015;37(1):88-99.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.