Evidence map›Paper›PMID 26503098›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2016

Intranasal Fentanyl Intoxication Leading to Diffuse Alveolar Hemorrhage.

Shannon Ruzycki, Mark Yarema, Michael Dunham, Hossein Sadrzadeh, Alain Tremblay

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Beyond respiratory depression: acute and delayed pulmonary responses following aerosolized fentanyl exposure.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
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  8. Fatalities caused by novel opioids: a review.Forensic sciences research · 2019
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shannon RuzyckiDepartment of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada. sarro@ualberta.ca.
Mark YaremaDepartment of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.
Michael DunhamDepartment of Critical Care Medicine, University of Calgary, Calgary, AB, Canada.
Hossein SadrzadehDepartment of Pathology and Laboratory Medicine, University of Calgary and Calgary Lab Services, Calgary, AB, Canada.
Alain TremblayDivision of Respiratory Medicine and Southern Alberta Cancer Research Institute, University of Calgary, Calgary, AB, Canada.
University of Calgary · CACalgary Laboratory Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextIncreasing rates of opioid abuse, particularly fentanyl, may lead to more presentations of unusual effects of opioid toxicity. Diffuse alveolar hemorrhage is a rare complication of fentanyl overdose. CASE DETAILS: A 45-year-old male presented in hypoxic respiratory failure secondary to diffuse alveolar hemorrhage requiring intubation. Comprehensive drug screening detected fentanyl without exposure to cocaine. Further history upon the patient's recovery revealed exposure to snorted fentanyl powder immediately prior to presentation. DISCUSSION: Diffuse alveolar hemorrhage is a potential, though rare, presentation of opioid intoxication.

conclusionsRecognition of less common complications of opioid abuse such as diffuse alveolar hemorrhage is important in proper management of overdoses.

Indexed as

Administration, InhalationAlbertaAnalgesics, OpioidCombined Modality TherapyDiagnosis, DifferentialDrug OverdoseFentanylHemorrhageHumansIntubation, IntratrachealLung Diseases, InterstitialMaleMiddle AgedOpioid-Related DisordersPowdersPulmonary AlveoliAnalgesics, OpioidFentanylPowdersDiffuse alveolar hemorrhageFentanylOpioid toxicityPulmonary hemorrhage

Identifiers

PMID26503098
PMCPMC4880598
OpenAlexW2272643829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.