Evidence map›Paper›PMID 26502996›Full record

ArticleChemical communications (Cambridge, England)2016

Croconaine rotaxane for acid activated photothermal heating and ratiometric photoacoustic imaging of acidic pH.

Samit Guha, Gillian Karen Shaw, Trevor M Mitcham, Richard R Bouchard, Bradley D Smith

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 88 citations in OpenAlex.

  1. Article
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  5. CuFeSACS applied materials & interfaces · 2023
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  8. Article
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  10. ACS nano · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Samit GuhaDepartment of Chemistry and Biochemistry, 236 Nieuwland Science Hall, University of Notre Dame, IN 46556, USA. smith.115@nd.edu.
Gillian Karen ShawDepartment of Chemistry and Biochemistry, 236 Nieuwland Science Hall, University of Notre Dame, IN 46556, USA. smith.115@nd.edu.
Trevor M MitchamDepartment of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Richard R BouchardDepartment of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Bradley D SmithDepartment of Chemistry and Biochemistry, 236 Nieuwland Science Hall, University of Notre Dame, IN 46556, USA. smith.115@nd.edu.
University of Notre Dame · USThe University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
PROMOTERS AND INHIBITORS OF MEMBRANE FUSIONR01GM059078 · NIGMS · UNIVERSITY OF NOTRE DAME · PI SMITH, BRADLEY D · 1999 to 2019
$5.8M
VisualSonics Vevo LAZR High-Resolution In Vivo Micro-Imaging SystemS10OD010403 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HAZLE, JOHN D. · 2012 to 2012
$596k
NCI NIH HHS P30 CA016672NIGMS NIH HHS GM059078NIGMS NIH HHS R01 GM059078NIH HHS S10 OD010403
6 · The paper itself

Abstract

Absorption of 808 nm laser light by liposomes containing a pH sensitive, near-infrared croconaine rotaxane dye increases dramatically in weak acid. A stealth liposome composition permits acid activated, photothermal heating and also acts as an effective nanoparticle probe for ratiometric photoacoustic imaging of acidic pH in deep sample locations, including a living mouse.

Indexed as

Photochemical ProcessesAcidsAnimalsColoring AgentsHot TemperatureHydrogen-Ion ConcentrationLightLiposomesMiceNanoparticlesPhotoacoustic TechniquesRotaxanesSpectrophotometry, UltravioletAcidsColoring AgentsLiposomesRotaxanes

Identifiers

PMID26502996
PMCPMC4679412
OpenAlexW1848855462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.