ArticleJournal of the American Chemical Society2015
Gelation Landscape Engineering Using a Multi-Reaction Supramolecular Hydrogelator System.
Article in Journal of the American Chemical Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Tridentate Coordination-Driven Covalent Organic Frameworks Incorporating Recycled Cobalt(II) for Enhanced Photocatalytic COSmall (Weinheim an der Bergstrasse, Germany) · 2026Article
- Catalytically controlled formation of coumarin-based hydrogelator enables colorimetric ferrous ion detection in sol and hydrogel.Communications chemistry · 2025Article
- Self-sorting and co-assembly control in multicomponent supramolecular hydrogels with dual monomer and polymer statistical distribution.Communications chemistry · 2025Article
- Cross-linking reactions in Langmuir monolayers of specially designed aminolipids - a toolbox for the customized production of amphiphilic nanosheets.Nanoscale advances · 2023Article
- Switching the Mode of Drug Release from a Reaction-Coupled Low-Molecular-Weight Gelator System by Altering Its Reaction Pathway.Biomacromolecules · 2023Article
- Control of seed formation allows two distinct self-sorting patterns of supramolecular nanofibers.Nature communications · 2020Article
- Catalytic Gels for a Prebiotically Relevant Asymmetric Aldol Reaction in Water: From Organocatalyst Design to Hydrogel Discovery and Back Again.Journal of the American Chemical Society · 2020Article
- Stability, Stimuli-Responsiveness, and Versatile Sorption Properties of a Dynamic Covalent Acylhydrazone Gel.Global challenges (Hoboken, NJ) · 2019Article
- Targetable Mechanical Properties by Switching between Self-Sorting and Co-assembly withChemNanoMat : chemistry of nanomaterials for energy, biology and more · 2018Article
- Water-Soluble Metalated Covalent Organic Nanobelts with Improved Bioavailability for Protein Transportation.Scientific reports · 2018Article
- Differential metal-binding properties of dynamic acylhydrazone polymers and their sensing applications.Royal Society open science · 2017Article
- Multiple competing pathways for chemical reaction: drastic reaction shortcut for the self-catalytic double-helix formation of helicene oligomers.Chemical science · 2017Article
- Substitution of Percutaneous Ethanol Injection with a Low Molecular Weight Peptide Gel Mimicking Chemoembolization for Cancer Therapy.Nanotheranostics · 2017Article
- Minimal C-terminal modification boosts peptide self-assembling ability for necroptosis of cancer cells.Chemical communications (Cambridge, England) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Simultaneous control of the kinetics and thermodynamics of two different types of covalent chemistry allows pathway selectivity in the formation of hydrogelating molecules from a complex reaction network. This can lead to a range of hydrogel materials with vastly different properties, starting from a set of simple starting compounds and reaction conditions. Chemical reaction between a trialdehyde and the tuberculosis drug isoniazid can form one, two, or three hydrazone connectivity products, meaning kinetic gelation pathways can be addressed. Simultaneously, thermodynamics control the formation of either a keto or an enol tautomer of the products, again resulting in vastly different materials. Overall, this shows that careful navigation of a reaction landscape using both kinetic and thermodynamic selectivity can be used to control material selection from a complex reaction network.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.