ReviewJournal of speech, language, and hearing research : JSLHR2016
Risk Factors Associated With Language in Autism Spectrum Disorder: Clues to Underlying Mechanisms.
Review in Journal of speech, language, and hearing research : JSLHR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 6 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Communicative Development Inventories (CDIs) in etiologically diverse developmental conditions: A systematic review.Research in developmental disabilities · 2026Pooled it
- Structural language profiles in children with autism spectrum disorder and developmental language disorder: a systematic review.Frontiers in psychology · 2026Pooled it
- Examining the Transition from Single Words to Phrase Speech in Children with ASD: A Systematic Review.Clinical child and family psychology review · 2024Pooled it
- Slower Processing Speed in Autism Spectrum Disorder: A Meta-analytic Investigation of Time-Based Tasks.Journal of autism and developmental disorders · 2023Pooled it
- Functional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review.American journal of speech-language pathology · 2020Pooled it
- The relation between parent verbal responsiveness and child communication in young children with or at risk for autism spectrum disorder: A systematic review and meta-analysis.Autism research : official journal of the International Society for Autism Research · 2019Pooled it
- Early Trajectories of Resting-State EEG power in autistic children: a longitudinal study across language profiles.Translational psychiatry · 2026Article
- Theta Power at 10 Months of Age Predicts Developmental Change in Language in Infants With and Without an Elevated Likelihood for Autism.Developmental science · 2026Article
- Altered aperiodic EEG spectral power during speech perception task is associated with verbal communication in youths with Autism Spectrum Disorder.bioRxiv : the preprint server for biology · 2025Article
- A common genetic variant in the Neurexin family member CNTNAP2 is related to language but not communication skills in youth with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2025Article
- Links Between Early Prelinguistic Communication and Later Expressive Language in Toddlers With Autistic and Non-Autistic Siblings.Journal of speech, language, and hearing research : JSLHR · 2025Article
- Active Play as a Window Into the Worlds of Twins and Triplets With Autism.Occupational therapy international · 2025Article
- Early trajectories and moderators of autistic language profiles: A longitudinal study in preschoolers.Autism : the international journal of research and practice · 2024Article
- The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives.Molecular autism · 2024Article
- Do focused interests support word learning? A study with autistic and nonautistic children.Autism research : official journal of the International Society for Autism Research · 2024Article
- Spatial Language and Cognition in Autistic Preschoolers.Journal of autism and developmental disorders · 2024Article
- Structural models of genome-wide covariance identify multiple common dimensions in autism.Nature communications · 2024Article
- Autism Prevalence Information And Diagnosis Processes In Cyprus, Greece And Malta.Neuropsychiatric disease and treatment · 2024Review
- Sex/Gender Differences in the Language Profiles of Italian Children with Autism Spectrum Disorder: A Retrospective Study.Journal of clinical medicine · 2023Article
- The Processing of Audiovisual Speech Is Linked with Vocabulary in Autistic and Nonautistic Children: An ERP Study.Brain sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purposeIdentifying risk factors associated with neurodevelopmental disorders is an important line of research, as it will lead to earlier identification of children who could benefit from interventions that support optimal developmental outcomes. The primary goal of this review was to summarize research on risk factors associated with autism spectrum disorder (ASD).
methodThe review focused on studies of infants who have older siblings with ASD, with particular emphasis on risk factors associated with language impairment that affects the majority of children with ASD. Findings from this body of work were compared to the literature on specific language impairment.
resultsA wide range of risk factors has been found for ASD, including demographic (e.g., male, family history), behavioral (e.g., gesture, motor) and neural risk markers (e.g., atypical lateralization for speech and reduced functional connectivity). Environmental factors, such as caregiver interaction, have not been found to predict language outcomes. Many of the risk markers for ASD are also found in studies of risk for specific language impairment, including demographic, behavioral, and neural factors.
conclusionsThere are significant gaps in the literature and limitations in the current research that preclude direct cross-syndrome comparisons. Future research directions are outlined that could address these limitations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.