ReviewInternational journal of molecular sciences2015
Genetics Underlying Atypical Parkinsonism and Related Neurodegenerative Disorders.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Article
- Article
- A microglia clonal inflammatory disorder in Alzheimer's Disease.bioRxiv : the preprint server for biology · 2024Article
- Application of Next-Generation Sequencing in Neurodegenerative Diseases: Opportunities and Challenges.Neuromolecular medicine · 2021Review
- Atypical parkinsonian syndromes in a North African tertiary referral center.Brain and behavior · 2021Article
- MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features.Acta neuropathologica communications · 2020Article
- DNAJC proteins and pathways to parkinsonism.The FEBS journal · 2019Review
- Assessment of APOE in atypical parkinsonism syndromes.Neurobiology of disease · 2019Article
- Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology.JAMA neurology · 2019Article
- Glucose metabolic brain patterns to discriminate amyotrophic lateral sclerosis from Parkinson plus syndromes.EJNMMI research · 2018Article
- Association study between multiple system atrophy and TREM2 p.R47H.Neurology. Genetics · 2018Article
- Paradigm for disease deconvolution in rare neurodegenerative disorders in Indian population: insights from studies in cerebellar ataxias.Journal of genetics · 2018Article
- Lysosomal storage disorder gene variants in multiple system atrophy.Brain : a journal of neurology · 2018Article
- Frontotemporal Lobe Degeneration as Origin of Scans Without Evidence of Dopaminergic Deficit.Frontiers in neurology · 2018Article
- Pseudohypoparathyroidism with basal ganglia calcification: A case report of rare cause of reversible parkinsonism.Medicine · 2017Article
- Next-generation sequencing reveals substantial genetic contribution to dementia with Lewy bodies.Neurobiology of disease · 2016Article
- C9orf72 Hexanucleotide Repeat Analysis in Cases with Pathologically Confirmed Dementia with Lewy Bodies.Neuro-degenerative diseases · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Atypical parkinsonism syndromes, such as dementia with Lewy bodies, multiple system atrophy, progressive supranuclear palsy and corticobasal degeneration, are neurodegenerative diseases with complex clinical and pathological features. Heterogeneity in clinical presentations, possible secondary determinants as well as mimic syndromes pose a major challenge to accurately diagnose patients suffering from these devastating conditions. Over the last two decades, significant advancements in genomic technologies have provided us with increasing insights into the molecular pathogenesis of atypical parkinsonism and their intriguing relationships to related neurodegenerative diseases, fueling new hopes to incorporate molecular knowledge into our diagnostic, prognostic and therapeutic approaches towards managing these conditions. In this review article, we summarize the current understanding of genetic mechanisms implicated in atypical parkinsonism syndromes. We further highlight mimic syndromes relevant to differential considerations and possible future directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.