Evidence map›Paper›PMID 26501232›Full record

ArticleMedicine and science in sports and exercise2016

Objective Sedentary Time, Moderate-to-Vigorous Physical Activity, and Physical Capability in a British Cohort.

Victoria L Keevil, Andrew J M Cooper, Katrien Wijndaele, Robert Luben, Nicholas J Wareham, Soren Brage, Kay-Tee Khaw

Abstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Association of sitting time and breaks in sitting with muscle mass, strength, function, and inflammation in community-dwelling older adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Trial
  3. Association of Physical Activity and Gait Speed: Does Context Matter?American journal of lifestyle medicine · 2026
    Article
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  17. Objective and subjective measurement of sedentary behavior in human adults: A toolkit.American journal of human biology : the official journal of the Human Biology Council · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victoria L Keevil1Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge, UNITED KINGDOM; and 2MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Addenbrookes Biomedical Campus, Cambridge, UNITED KINGDOM.
Andrew J M Cooper
Katrien Wijndaele
Robert Luben
Nicholas J Wareham
Soren Brage
Kay-Tee Khaw

Funding

British Heart Foundation FS/12/58/29709Cancer Research UK A8257Cancer Research UK C864/A8257Medical Research Council G0401527Medical Research Council G1000143Medical Research Council G9502233Medical Research Council MC_U106179471Medical Research Council MC_U106179473Medical Research Council MC_UU_12015/1Medical Research Council MC_UU_12015/3Medical Research Council MC_UU_12015/4Wellcome Trust 092077Wellcome Trust 092077/Z/10/Z
6 · The paper itself

Abstract

purposeSedentariness has been proposed as an independent risk factor for poor health. However, few studies have considered associations of sedentary time (ST) with physical functional health independent of time spent in moderate-to-vigorous physical activity (MVPA).

methodsCommunity-based men and women (n = 8623, 48-92 yr old) in the European Prospective Investigation of Cancer-Norfolk study attended a health examination for objective measurement of physical capability, including grip strength (Smedley dynamometer (kg)), usual walking speed (UWS (cm·s(-1))), and timed chair stand speed (TCSS (stands per minute)). Of these, 4051 participants wore an accelerometer (GT1M ActiGraph) for 7 d to estimate time spent in MVPA (MVPA, ≥1952 counts per minute) and ST (ST, <100 counts per minute). Relations between physical capability outcomes and both MVPA and ST were explored using linear regression. The mutual independence of associations was also tested, and ST-MVPA interactions were explored using fractional polynomial models to account for nonlinear associations.

resultsMen in the highest compared with those in the lowest sex-specific quartile of MVPA were stronger (1.84 kg; 95% confidence interval (CI), 0.79-2.89), had faster UWS (11.7 cm·s(-1); 95% CI, 8.4-15.1) and faster TCSS (2.35 stands per minute; 95% CI, 1.11-3.59) after multivariable adjustment. Similarly, women in the highest quartile of MVPA were stronger (2.47 kg; 95% CI, 1.79-3.14) and had faster UWS (15.5 cm·s(-1); 95% CI, 12.4-18.6) and faster TCSS (3.27 stands per minute; 95% CI, 2.19-4.25). Associations persisted after further adjustment for ST. Associations between higher ST and lower physical capability were also observed, but these were attenuated after accounting for MVPA. Furthermore, no MVPA-ST interactions were observed (Pinteractions > 0.05).

conclusionsMore time spent in MVPA was associated with higher physical capability, but there were no independent ST associations.

Indexed as

AgingExerciseSedentary BehaviorAccelerometryAgedAged, 80 and overCross-Sectional StudiesExercise TestFemaleHand StrengthHumansMaleMiddle AgedPostural BalanceProspective StudiesRisk Factors

Identifiers

PMID26501232
PMCPMC4762192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.