ArticleJournal of alcoholism and drug dependence2015
Platelets Contribute to BBB Disruption Induced by HIV and Alcohol.
Article in Journal of alcoholism and drug dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Analysis of Manifestations and Associated Factors of HIV-1 Associated Thrombocytopenia in a General Teaching Hospital in Western China.Infection and drug resistance · 2025Article
- Blood-brain barrier permeability in survivors of immune-mediated thrombotic thrombocytopenic purpura: a pilot study.Blood advances · 2021Article
- Inflammatory Mechanisms and Cascades Contributing to Neurocognitive Impairment in HIV/AIDS.Current topics in behavioral neurosciences · 2021Article
- Thrombin disrupts vascular endothelial-cadherin and leads to hydrocephalus via protease-activated receptors-1 pathway.CNS neuroscience & therapeutics · 2019Article
- Novel Antiretroviral Structures from Marine Organisms.Molecules (Basel, Switzerland) · 2019Review
- Restraint Stress Induced Hyperpermeability and Damage of the Blood-Brain Barrier in the Amygdala of Adult Rats.Frontiers in molecular neuroscience · 2019Article
- Article
- Effects of docosahexaenoic acid on locomotor activity in ethanol-treated HIV-1 transgenic rats.Journal of neurovirology · 2018Article
- Modeling HIV-1 Induced Neuroinflammation in Mice: Role of Platelets in Mediating Blood-Brain Barrier Dysfunction.PloS one · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The role of platelets in the neurological diseases that underlie cognitive impairment has attracted increasing attention in recent years. Multiple pathways in platelets contribute to host defenses, as well as to CNS function. In the current study, we hypothesize that the Blood Brain Barrier (BBB) is disrupted when exposed to platelets from patients with triple Co-morbidity (hazardous alcohol users+ HIV+ thrombocytopenia), compared to those with dual, single or no morbidity (HIV only, alcohol only or healthy controls).
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Registered trials
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