Evidence map›Paper›PMID 26500852›Full record

ArticleJournal of neonatal surgery

Feeding Intolerance and Poor Growth in Infants with Gastroschisis: Longitudinal Experience with Consecutive Patients over Thirteen Years.

Saloni Balgi, Sarita Singhal, Georgia Mueller, Beau Batton

Registry-linked trialAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of neonatal surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03393832 (Oral Care), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03393832 active not recruitingnot on this map

Oral Care: An Important Adjunctive Therapy to Improve Feeding Tolerance in Infants With Gastroschisis

TypeobservationalSponsorBaylor College of MedicineRan2017 to 2026Enrolled27ConditionsGastroschisis
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Abdominal Wall Defects-Current Treatments.Children (Basel, Switzerland) · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saloni BalgiDepartment of Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois.
Sarita SinghalDepartment of Pediatrics, University of Buffalo School of Medicine, Buffalo, New York.
Georgia MuellerStatistics & Epidemiology, Southern Illinois University School of Medicine, Springfield, Illinois.
Beau BattonDepartment of Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives1) To investigate in-hospital factors associated with delayed tolerance of full volume enteral nutrition and 2) To assess longitudinal growth in a contemporary population of infants with gastroschisis.

designRetrospective single-center study of all infants with gastroschisis Setting: Level III neonatal intensive care unit in a free-standing Children's Hospital Duration: 13.5 years MATERIALS &

methodsDetailed data regarding demographics, nutritional support, growth, and infant outcomes was collected for all infants with gastroschisis. Linear regression was used to investigate in-hospital factors associated with feeding intolerance and poor growth.

resultsFor 52 infants, the median gestational age at birth was 36 weeks, the median postnatal age to achieve full feeds was 22 days, and median in-hospital weight gain was 18 gm/day. With linear regression, there was a positive association between time to full feeds and both hospital length of stay (adjusted R2=0.503, p < 0.0001) and (unexpectedly) in-hospital weight gain (adjusted R2=0.125, p=0.0248). There was a negative association between in-hospital weight gain and preterm birth (adjusted R2=0.125, p=0.0356). For infants with longitudinal growth data, 35% had a weight < 5th percentile (of whom 67% were preterm).

conclusionsMany infants with gastroschisis have poor growth before and after hospital discharge. Aggressive feeding advancement may be a contributing factor to this finding and preterm infants may be at greater risk for poor growth than term infants.

Indexed as

Enteral nutritionGastroschisisGrowthPreterm infant

Identifiers

PMID26500852
PMCPMC4617017

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.