Evidence map›Paper›PMID 26500808›Full record

ArticleClinical advances in periodontics2011

Future Prospects for Periodontal Bioengineering Using Growth Factors.

William V Giannobile, Scott J Hollister, Peter X Ma

Abstract read
In one paragraph

Article in Clinical advances in periodontics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

William V GiannobileDepartment of Periodontics and Oral Medicine and Michigan Center for Oral Health Research, School of Dentistry, University of Michigan, Ann Arbor, MI.
Scott J HollisterDepartment of Biomedical Engineering, College of Engineering, University of Michigan.
Peter X MaDepartment of Biomedical Engineering, College of Engineering, University of Michigan.
University of Michigan–Ann Arbor · US

Funding

GENE THERAPY FOR RECONSTRUCTING PERIODONTAL TISSUESR01DE013397 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIANNOBILE, WILLIAM V · 2000 to 2014
$4.0M
Periodontal Engineering Using Biomimetic Nano ScaffoldsR01DE015384 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MA, PETER X · 2003 to 2011
$2.9M
National Institutes of Health/National Institute of Dental and Craniofacial Research DE 015384National Institutes of Health/National Institute of Dental and Craniofacial Research DE 13397-10NIDCR NIH HHS R01 DE013397NIDCR NIH HHS R01 DE015384
6 · The paper itself

Abstract

Polypeptide growth factors have demonstrated strong potential to repair defects associated with teeth and dental implants. Over the past two decades, intense research efforts have led to the clinical development of several growth factors or biologic agents, including bone morphogenetic proteins, platelet-derived growth factor, fibroblast growth factors, and enamel matrix proteins. Several of these growth factors are now being used clinically for a variety of applications, such as the promotion of periodontal regeneration, sinus floor augmentation, and root coverage procedures. Although clinical results have been promising and growth factors add another dimension to clinical care, optimization of growth factor targeting approaches to periodontal wounds remains a challenge. Enhancement of growth factor local application to improve bioavailability, bioactivity, and allowance of three-dimensional reconstruction of complex anatomic defects is a goal. This article will highlight developments for growth factor delivery to better stimulate the wound healing response for periodontal and bone regeneration in the maxillofacial region.

Indexed as

Bone morphogenetic proteinsfibroblast growth factorsplatelet-derived growth factorregenerationregenerative medicinetissue engineering

Identifiers

PMID26500808
PMCPMC4617553
OpenAlexW2120611253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.