Evidence map›Paper›PMID 26500721›Full record

ArticleNano research2014

Glyconanomaterials: Emerging applications in biomedical research.

Xuan Chen, Olof Ramström, Mingdi Yan

Abstract read
In one paragraph

Article in Nano research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. MRI Contrast Agents in Glycobiology.Molecules (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Glyco-nanotechnology: A biomedical perspective.Nanomedicine : nanotechnology, biology, and medicine · 2022
    Review
  8. Article
  9. Review
  10. Quantification of binding affinity of glyconanomaterials with lectins.Chemical communications (Cambridge, England) · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Glyconanomaterials for biosensing applications.Biosensors & bioelectronics · 2016
    Review
  16. Article
  17. Glyconanomaterials for Combating Bacterial Infections.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xuan ChenDepartment of Chemistry, University of Massachusetts Lowell, Lowell, MA 01854, USA.
Olof RamströmDepartment of Chemistry, KTH-Royal Institute of Technology, Stockholm S-10044, Sweden.
Mingdi YanDepartment of Chemistry, University of Massachusetts Lowell, Lowell, MA 01854, USA ; Department of Chemistry, KTH-Royal Institute of Technology, Stockholm S-10044, Sweden.

Funding

Photogenerated Carbohydrate MicroarraysR01GM080295 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2008 to 2012
$2.0M
Surface Chemistry for Immobilization of Ultrathin FilmsR15GM066279 · NIGMS · PORTLAND STATE UNIVERSITY · PI YAN, MINGDI · 2005 to 2008
$410k
NIGMS NIH HHS R01 GM080295NIGMS NIH HHS R15 GM066279
6 · The paper itself

Abstract

Carbohydrates constitute the most abundant organic matter in nature, serving as structural components and energy sources, and mediating a wide range of cellular activities. The emergence of nanomaterials with distinct optical, magnetic, and electronic properties has witnessed a rapid adoption of these materials for biomedical research and applications. Nanomaterials of various shapes and sizes having large specific surface areas can be used as multivalent scaffolds to present carbohydrate ligands. The resulting glyconanomaterials effectively amplify the glycan-mediated interactions, making it possible to use these materials for sensing, imaging, diagnosis, and therapy. In this review, we summarize the synthetic strategies for the preparation of various glyconanomaterials. Examples are given where these glyconanomaterials have been used in sensing and differentiation of proteins and cells, as well as in imaging glycan-medicated cellular responses.

Indexed as

carbohydratesglyconanomaterialsimagingtherapy

Identifiers

PMID26500721
PMCPMC4617207

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.