ArticleBiotechnology for biofuels2015
Phylogeny-structured carbohydrate metabolism across microbiomes collected from different units in wastewater treatment process.
Article in Biotechnology for biofuels, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Rice straw increases microbial nitrogen fixation, bacterial andFrontiers in microbiology · 2023Article
- Land-Use Change and Management Intensification Is Associated with Shifts in Composition of Soil Microbial Communities and Their Functional Diversity in Coffee Agroecosystems.Microorganisms · 2022Article
- Metagenomics approach to the study of the gut microbiome structure and function in zebrafish Danio rerio fed with gluten formulated diet.Journal of microbiological methods · 2017Article
- Article
- Diversity of microbial carbohydrate-active enzymes in Danish anaerobic digesters fed with wastewater treatment sludge.Biotechnology for biofuels · 2017Article
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4 authors.
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Abstract
backgroundWith respect to global priority for bioenergy production from plant biomass, understanding the fundamental genetic associations underlying carbohydrate metabolisms is crucial for the development of effective biorefinery process. Compared with gut microbiome of ruminal animals and wood-feed insects, knowledge on carbohydrate metabolisms of engineered biosystems is limited.
resultsIn this study, comparative metagenomics coupled with metabolic network analysis was carried out to study the inter-species cooperation and competition among carbohydrate-active microbes in typical units of wastewater treatment process including activated sludge and anaerobic digestion. For the first time, sludge metagenomes demonstrated rather diverse pool of carbohydrate-active genes (CAGs) comparable to that of rumen microbiota. Overall, the CAG composition correlated strongly with the microbial phylogenetic structure across sludge types. Gene-centric clustering analysis showed the carbohydrate pathways of sludge systems were shaped by different environmental factors, including dissolved oxygen and salinity, and the latter showed more determinative influence of phylogenetic composition. Eventually, the highly clustered co-occurrence network of CAGs and saccharolytic phenotypes, revealed three metabolic modules in which the prevalent populations of Actinomycetales, Clostridiales and Thermotogales, respectively, play significant roles as interaction hubs, while broad negative co-exclusion correlations observed between anaerobic and aerobic microbes, probably implicated roles of niche separation by dissolved oxygen in determining the microbial assembly.
conclusionsSludge microbiomes encoding diverse pool of CAGs was another potential source for effective lignocellulosic biomass breakdown. But unlike gut microbiomes in which Clostridiales, Lactobacillales and Bacteroidales play a vital role, the carbohydrate metabolism of sludge systems is built on the inter-species cooperation and competition among Actinomycetales, Clostridiales and Thermotogales.
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