ArticleHepatitis monthly2015
Five Years Survival of Patients After Liver Transplantation and Its Effective Factors by Neural Network and Cox Poroportional Hazard Regression Models.
Article in Hepatitis monthly, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Sarcopenia and frailty: An in-depth analysis of the pathophysiology and effect on liver transplant candidates.World journal of hepatology · 2025Review
- Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients.Scientific reports · 2025Article
- Advanced omics approaches in liver transplant settings: current applications and future prospectives.Frontiers in immunology · 2025Review
- Article
- Pediatric and adult liver transplantation in Bahrain: The experiences in a country with no available liver transplant facilities.World journal of transplantation · 2024Article
- Artificial Intelligence in Liver Diseases: Recent Advances.Advances in therapy · 2024Review
- Spatial inequalities and non-linear association of continuous variables with mortality risk of liver transplantation in Iran: a retrospective cohort study.Scientific reports · 2024Article
- Should AI allocate livers for transplant? Public attitudes and ethical considerations.BMC medical ethics · 2023Article
- Application of machine learning in liver transplantation: a review.Hepatology international · 2022Review
- Review
- The digital transformation of hepatology: The patient is logged in.Hepatology (Baltimore, Md.) · 2022Review
- Artificial Intelligence and the Future of Gastroenterology and Hepatology.Gastro hep advances · 2022Review
- Artificial Intelligence for Understanding Imaging, Text, and Data in Gastroenterology.Gastroenterology & hepatology · 2020Article
- Barriers to Adherence to Medical Care Programs in Liver Transplant Recipients: A Qualitative Study.International journal of organ transplantation medicine · 2019Article
- Molecular Subtyping of Serous Ovarian Cancer Based on Multi-omics Data.Scientific reports · 2016Article
- Identifying the Prognosis Factors in Death after Liver Transplantation via Adaptive LASSO in Iran.Journal of environmental and public health · 2016Article
- Artificial Intelligence in Hepatology- Ready for the Primetime.Journal of clinical and experimental hepatologyReview
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5 authors.
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Abstract
backgroundTransplantation is the only treatment for patients with liver failure. Since the therapy imposes high expenses to the patients and community, identification of effective factors on survival of such patients after transplantation is valuable.
objectivesThe current study attempted to model the survival of patients (two years old and above) after liver transplantation using neural network and Cox Proportional Hazards (Cox PH) regression models. The event is defined as death due to complications of liver transplantation. PATIENTS AND
methodsIn a historical cohort study, the clinical findings of 1168 patients who underwent liver transplant surgery (from March 2008 to march 2013) at Shiraz Namazee Hospital Organ Transplantation Center, Shiraz, Southern Iran, were used. To model the one to five years survival of such patients, Cox PH regression model accompanied by three layers feed forward artificial neural network (ANN) method were applied on data separately and their prediction accuracy was compared using the area under the receiver operating characteristic curve (ROC). Furthermore, Kaplan-Meier method was used to estimate the survival probabilities in different years.
resultsThe estimated survival probability of one to five years for the patients were 91%, 89%, 85%, 84%, and 83%, respectively. The areas under the ROC were 86.4% and 80.7% for ANN and Cox PH models, respectively. In addition, the accuracy of prediction rate for ANN and Cox PH methods was equally 92.73%.
conclusionsThe present study detected more accurate results for ANN method compared to those of Cox PH model to analyze the survival of patients with liver transplantation. Furthermore, the order of effective factors in patients' survival after transplantation was clinically more acceptable. The large dataset with a few missing data was the advantage of this study, the fact which makes the results more reliable.
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