Trial reportJournal of the International Society of Sports Nutrition2015
A high protein diet (3.4 g/kg/d) combined with a heavy resistance training program improves body composition in healthy trained men and women--a follow-up investigation.
Trial report in Journal of the International Society of Sports Nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A systematic review of interventions targeting modifiable factors that impact dietary intake in athletes.The British journal of nutrition · 2024Pooled it
- High-protein diets and testosterone.Nutrition and health · 2023Pooled it
- Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults.Journal of cachexia, sarcopenia and muscle · 2022Pooled it
- A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults.British journal of sports medicine · 2018Pooled it
- Resistance versus concurrent training with three assigned protein targets in middle-aged and older women: a randomized 2 × 3 factorial trial.Journal of the International Society of Sports Nutrition · 2026Trial
- Hypercaloric 16:8 time-restricted eating during 8 weeks of resistance exercise in well-trained men and women.Journal of the International Society of Sports Nutrition · 2025Trial
- Trial
- Satiating Effect of High Protein Diets on Resistance-Trained Subjects in Energy Deficit.Nutrients · 2018Trial
- High protein consumption in trained women: bad to the bone?Journal of the International Society of Sports Nutrition · 2018Trial
- Trial
- The short-term effect of high versus moderate protein intake on recovery after strength training in resistance-trained individuals.Journal of the International Society of Sports Nutrition · 2017Trial
- Protein-Pacing and Multi-Component Exercise Training Improves Physical Performance Outcomes in Exercise-Trained Women: The PRISE 3 Study.Nutrients · 2016Trial
- The effects of a high protein diet on indices of health and body composition--a crossover trial in resistance-trained men.Journal of the International Society of Sports Nutrition · 2016Trial
- The effects of whey protein with or without carbohydrates on resistance training adaptations.Journal of the International Society of Sports Nutrition · 2015Trial
- Common questions and misconceptions about diets: what does the scientific evidence really show?Journal of the International Society of Sports Nutrition · 2026Review
- International Society of Sports Nutrition position stand: diets for body weight reduction.Journal of the International Society of Sports Nutrition · 2026Review
- Comparison of two nutritional protocols in body re-composition of resistance-trained participants.European journal of applied physiology · 2026Article
- The Role of Nutrition in Exercise and Sports.Nutrients · 2026Article
- The Crucial Role of Exercise in Promoting Adolescent Bone Health.Advances in experimental medicine and biology · 2026Review
- Nutritional Supplements for Muscle Hypertrophy: Mechanisms and Morphology-Focused Evidence.Nutrients · 2025Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe consumption of a high protein diet (>4 g/kg/d) in trained men and women who did not alter their exercise program has been previously shown to have no significant effect on body composition. Thus, the purpose of this investigation was to determine if a high protein diet in conjunction with a periodized heavy resistance training program would affect indices of body composition, performance and health.
methodsForty-eight healthy resistance-trained men and women completed this study (mean ± SD; Normal Protein group [NP n = 17, four female and 13 male]: 24.8 ± 6.9 yr; 174.0 ± 9.5 cm height; 74.7 ± 9.6 kg body weight; 2.4 ± 1.7 yr of training; High Protein group [HP n = 31, seven female and 24 male]: 22.9 ± 3.1 yr; 172.3 ± 7.7 cm; 74.3 ± 12.4 kg; 4.9 ± 4.1 yr of training). Moreover, all subjects participated in a split-routine, periodized heavy resistance-training program. Training and daily diet logs were kept by each subject. Subjects in the NP and HP groups were instructed to consume their baseline (~2 g/kg/d) and >3 g/kg/d of dietary protein, respectively.
resultsSubjects in the NP and HP groups consumed 2.3 and 3.4 g/kg/day of dietary protein during the treatment period. The NP group consumed significantly (p < 0.05) more protein during the treatment period compared to their baseline intake. The HP group consumed more (p < 0.05) total energy and protein during the treatment period compared to their baseline intake. Furthermore, the HP group consumed significantly more (p < 0.05) total calories and protein compared to the NP group. There were significant time by group (p ≤ 0.05) changes in body weight (change: +1.3 ± 1.3 kg NP, -0.1 ± 2.5 HP), fat mass (change: -0.3 ± 2.2 kg NP, -1.7 ± 2.3 HP), and % body fat (change: -0.7 ± 2.8 NP, -2.4 ± 2.9 HP). The NP group gained significantly more body weight than the HP group; however, the HP group experienced a greater decrease in fat mass and % body fat. There was a significant time effect for FFM; however, there was a non-significant time by group effect for FFM (change: +1.5 ± 1.8 NP, +1.5 ± 2.2 HP). Furthermore, a significant time effect (p ≤ 0.05) was seen in both groups vis a vis improvements in maximal strength (i.e., 1-RM squat and bench) vertical jump and pull-ups; however, there were no significant time by group effects (p ≥ 0.05) for all exercise performance measures. Additionally, there were no changes in any of the blood parameters (i.e., basic metabolic panel).
conclusionConsuming a high protein diet (3.4 g/kg/d) in conjunction with a heavy resistance-training program may confer benefits with regards to body composition. Furthermore, there is no evidence that consuming a high protein diet has any deleterious effects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.