Evidence map›Paper›PMID 26500458›Full record

ArticleThrombosis journal2015

The management of acute venous thromboembolism in clinical practice - study rationale and protocol of the European PREFER in VTE Registry.

Giancarlo Agnelli, Anselm K Gitt, Rupert Bauersachs, Eva-Maria Fronk, Petra Laeis, Patrick Mismetti, Manuel Monreal, Stefan N Willich, Wolf-Peter Wolf, Alexander T Cohen and 1 more

Abstract read
In one paragraph

Article in Thrombosis journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Quality of life in oncological patients with venous thromboembolic disease.Research and practice in thrombosis and haemostasis · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Rationale, design and methodology of TESEO study: a registry of thrombosis and neoplasia of SEOM (Spanish Society of Medical Oncology).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  7. Health-related quality of life and mortality in patients with pulmonary embolism: a prospective cohort study in seven European countries.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  8. Comparison of quality of life measurements: EQ-5D-5L versus disease/treatment-specific measures in pulmonary embolism and deep vein thrombosis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The impact of co-morbidity on the disease burden of VTE.Journal of thrombosis and thrombolysis · 2018
    Article
  14. Article
  15. Observational
  16. Review
  17. Observational
  18. Direct oral anticoagulants and venous thromboembolism.European respiratory review : an official journal of the European Respiratory Society · 2016
    Review
  19. Review
  20. Deep Vein Thrombosis in Europe-Health-Related Quality of Life and Mortality.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giancarlo AgnelliUniversity of Perugia, Santa Maria della Misericordia Hospital, Perugia, Italy.
Anselm K GittHerzzentrum Ludwigshafen Med. Klinik B, Ludwigshafen, Germany.
Rupert BauersachsKlinikum Darmstadt GmbH, Darmstadt, Center of Thrombosis and Hemostasis, University of Mainz, Mainz, Germany ; Center of Thrombosis and Haemostasis, University of Mainz, Mainz, Germany.
Eva-Maria FronkDaiichi Sankyo Europe GmbH, Munich, Germany.
Petra LaeisDaiichi Sankyo Europe GmbH, Munich, Germany.
Patrick MismettiCHU Saint-Etienne Hopital Nord, Saint Etienne, Cedex 2 France.
Manuel MonrealHospital Universitari Germans Trias i Pujol, Barcelona, Spain.
Stefan N WillichCharité - Universitätsmedizin Berlin, Berlin, Germany.
Wolf-Peter WolfCenter of Thrombosis and Haemostasis, University of Mainz, Mainz, Germany.
Alexander T CohenKing's College, Guys and St Thomas' Hospitals NHS Foundation Trust, Westminster Bridge Road, London, SE1 7EH UK.
PREFER in VTE investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVenous thromboembolism (VTE) is a major health problem, with over one million events every year in Europe. However, there is a paucity of data on the current management in real life, including factors influencing treatment pathways, patient satisfaction, quality of life (QoL), and utilization of health care resources and the corresponding costs. The PREFER in VTE registry has been designed to address this and to understand medical care and needs as well as potential gaps for improvement. METHODS/

designThe PREFER in VTE registry was a prospective, observational, multicenter study conducted in seven European countries including Austria, France Germany, Italy, Spain, Switzerland, and the UK to assess the characteristics and the management of patients with VTE, the use of health care resources, and to provide data to estimate the costs for 12 months treatment following a first-time and/or recurrent VTE diagnosed in hospitals or specialized or primary care centers. In addition, existing anticoagulant treatment patterns, patient pathways, clinical outcomes, treatment satisfaction, and health related QoL were documented. The centers were chosen to reflect the care environment in which patients with VTE are managed in each of the participating countries. Patients were eligible to be enrolled into the registry if they were at least 18 years old, had a symptomatic, objectively confirmed first time or recurrent acute VTE defined as either distal or proximal deep vein thrombosis, pulmonary embolism or both. After the baseline visit at the time of the acute VTE event, further follow-up documentations occurred at 1, 3, 6 and 12 months. Follow-up data was collected by either routinely scheduled visits or by telephone calls.

resultsOverall, 381 centers participated, which enrolled 3,545 patients during an observational period of 1 year.

conclusionThe PREFER in VTE registry will provide valuable insights into the characteristics of patients with VTE and their acute and mid-term management, as well as into drug utilization and the use of health care resources in acute first-time and/or recurrent VTE across Europe in clinical practice.

trial registrationRegistered in DRKS register, ID number: DRKS00004795.

Indexed as

AnticoagulationNovel Oral AnticoagulantsPreventionRegistryVenous ThromboembolismVitamin K antagonists

Identifiers

PMID26500458
PMCPMC4618861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.