SynthesisBMC ophthalmology2015
Central corneal sensitivity after small incision lenticule extraction versus femtosecond laser-assisted LASIK for myopia: a meta-analysis of comparative studies.
Synthesis in BMC ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Pooled it
- Pooled it
- Utilising VISULYZE-Generated Nomograms and OcuLign Alignment Tools to Improve Keratorefractive Lenticule Extraction Outcomes.Journal of clinical medicine · 2026Article
- Real-World Study Assessing the Efficacy and Safety of a Novel KLEx Procedure with a Next-Generation Femtosecond Laser for Refractive Error Correction.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Hyperopic keratorefractive lenticule extraction.Journal of cataract and refractive surgery · 2026Review
- Effects of different side-cut angles on ocular surface recovery after FS-LASIK.International journal of ophthalmology · 2026Article
- Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery.Clinical proteomics · 2024Article
- Refractive surgery and dry eye - An update.Indian journal of ophthalmology · 2023Review
- Comparison of clinical outcomes of LASIK, Trans-PRK, and SMILE for correction of myopia.Journal of the Chinese Medical Association : JCMA · 2022Article
- Prospective, Randomized, Fellow Eye-Controlled Study of Postoperative Pain and Inflammation Control with an Intracanalicular Dexamethasone 0.4 mg Ophthalmic Insert Following Small Incision Lenticule Extraction.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Ocular Surface Changes Associated with Ophthalmic Surgery.Journal of clinical medicine · 2021Review
- Impact of corneal refractive surgery on the precorneal tear film.Indian journal of ophthalmology · 2020Review
- Complications of small incision lenticule extraction.Indian journal of ophthalmology · 2020Review
- Comparison of Visual, Refractive and Ocular Surface Outcomes Between Small Incision Lenticule Extraction and Laser-Assisted In Situ Keratomileusis for Myopia and Myopic Astigmatism.Ophthalmology and therapy · 2019Review
- Corneal re-innervation following refractive surgery treatments.Neural regeneration research · 2019Review
- Refractive lenticule extraction small incision lenticule extraction: A new refractive surgery paradigm.Indian journal of ophthalmology · 2018Review
- A review and meta-analysis of corneal cross-linking for post-laser vision correction ectasia.Journal of current ophthalmology · 2017Review
- Dry eye and corneal sensitivity after small incision lenticule extraction and femtosecond laser-assistedInternational journal of ophthalmology · 2017Article
- Review on Centration, Astigmatic Axis Alignment, Pupil Size and Optical Zone in SMILE.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Review
- Dry Eyes After SMILE.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate central corneal sensitivity after small incision lenticule extraction (SMILE) versus femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia.
methodsEligible studies were identified by systematically searching PubMed, the Cochrane Library, Embase and the Chinese Biomedicine Database. Central corneal sensitivity after SMILE versus FS-LASIK was assessed by the pooled weighted mean differences (WMDs) of the reduction from pre-operation levels to 1 week, 1, 3 and 6 months following the operation. The quality of the included literature was assessed by the Quality Index. Data were synthesized by Stata 12.0 SE for Windows.
resultsFive studies involving 245 patients (363 eyes; 189 eyes in the FS-LASIK group and 174 eyes in the SMILE group) were included in the meta-analysis. The pooled results showed that there were no significant differences in central corneal sensitivity between FS-LASIK and SMILE before surgery (WMD = 0 mm, 95 % CI: -0.23 to -0.23, p = 0.998). At 1 week, 1 and 3 months after surgery, the central corneal sensitivity after FS-LASIK was lower than with SMILE (WMD = -17.35 mm, 95 % CI: -26.54 to -8.16, p <0.001; WMD = -17.52 mm, 95 % CI: -25.10 to -9.94, p <0.001; WMD = -14.64 mm, 95 % CI: -20.08 to -9.21, p <0.001, respectively). However, central corneal sensitivity after FS-LASIK was similar with SMILE 6 months after surgery (WMD = -2.02 mm, 95 % CI: -4.23 to 0.19, p = 0.074).
conclusionCentral corneal sensitivity exhibited a small decrease and a faster recovery after the SMILE procedure compared to FS-LASIK during the first three postoperative months. Corneal sensitivity after SMILE and FS-LASIK was similar at 6 months after surgery. However, these results should be interpreted with caution due to the limited number of studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.