Evidence map›Paper›PMID 26499492›Full record

ArticleeLife2015

cryo-EM structures of the

Rafael Fernandez-Leiro, Julian Conrad, Sjors Hw Scheres, Meindert H Lamers

Open access · goldAbstract read
In one paragraph

Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Review
  3. Mechanistic diversity of clamp loading at small DNA gaps.The Journal of biological chemistry · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. ThebioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Small molecules targeting the eubacterial β-sliding clamp discovered by combinedJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  11. Review
  12. A bipartite interaction with the processivity clamp potentiates Pol IV-mediated TLS.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rafael Fernandez-LeiroMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0002-7941-0357
Julian ConradMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Sjors Hw ScheresMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0002-0462-6540
Meindert H LamersMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
MRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_U105197143Medical Research Council MC_UP_A025_1013
6 · The paper itself

Abstract

The replicative DNA polymerase PolIIIα from

Indexed as

biophysicscryo-EMDNA repairDNA replicationE. colistructural biology

Identifiers

PMID26499492
PMCPMC4703070
OpenAlexW2192151631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.