Evidence map›Paper›PMID 26499281›Full record

ReviewMagnetic resonance imaging clinics of North America2015

Magnetic Resonance-Guided Drug Delivery.

Andrew S Mikhail, Ari Partanen, Pavel Yarmolenko, Aradhana M Venkatesan, Bradford J Wood

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Magnetic resonance imaging clinics of North America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Precision Oncology: Advances in Drug Delivery and Imaging.Recent advances in drug delivery and formulation · 2025
    Review
  2. Article
  3. International journal of molecular sciences · 2023
    Article
  4. Article
  5. Tissue-mimicking thermochromic phantom for characterization of HIFU devices and applications.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Andrew S MikhailCenter for Interventional Oncology, Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA.
Ari PartanenCenter for Interventional Oncology, Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA; Philips Healthcare, 3000 Minuteman Road, Andover, MA 01810, USA.
Pavel YarmolenkoThe Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Medical Center, 111 Michigan Avenue, Washington, DC 20010, USA.
Aradhana M VenkatesanSection of Abdominal Imaging, Department of Diagnostic Radiology, M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030-4009, USA.
Bradford J WoodCenter for Interventional Oncology, Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address: bwood@nih.gov.
National Institutes of Health Clinical Center · USChildren's National · USPhilips (United States) · USThe University of Texas MD Anderson Cancer Center · US

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
Image Guided Focused Ultrasound For Drug Delivery and Tissue AblationZ01CL040012 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2008 to 2008
$33k
Navigation Tools for Image Guided Minimally invasive TherapiesZIACL040011 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
Image Guided Focused Ultrasound For Drug Delivery and Tissue AblationZIACL040012 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2024
$0k
Interventional OncologyZIACL040015 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
CLC NIH HHS Z1A CL040015-06Intramural NIH HHS Z01 CL040012Intramural NIH HHS ZIA CL040015
6 · The paper itself

Abstract

The use of clinical imaging modalities for the guidance of targeted drug delivery systems, known as image-guided drug delivery (IGDD), has emerged as a promising strategy for enhancing antitumor efficacy. MR imaging is particularly well suited for IGDD applications because of its ability to acquire images and quantitative measurements with high spatiotemporal resolution. The goal of IGDD strategies is to improve treatment outcomes by facilitating planning, real-time guidance, and personalization of pharmacologic interventions. This article reviews basic principles of targeted drug delivery and highlights the current status, emerging applications, and future paradigms of MR-guided drug delivery.

Indexed as

Drug Delivery SystemsHumansMagnetic Resonance Imaging, InterventionalCancerDrug deliveryHigh-intensity focused ultrasoundImaging guidanceMR imagingNanomedicineThermosensitive liposomeTumor targeting

Identifiers

PMID26499281
PMCPMC5580964
OpenAlexW1874527557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.