ArticleChemical communications (Cambridge, England)2016
Expanding the scope of alkyne-mediated bioconjugations utilizing unnatural amino acids.
Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Hydrochalcogenation Reactions with Noncanonical Amino Acids as a Route to Increase Bioconjugate Valency.ACS omega · 2025Article
- Employing non-canonical amino acids towards the immobilization of a hyperthermophilic enzyme to increase protein stability.RSC advances · 2023Article
- Efficient Selection Scheme for Incorporating Noncanonical Amino Acids Into Proteins inFrontiers in bioengineering and biotechnology · 2020Article
- Mechanistic investigation and further optimization of the aqueous Glaser-Hay bioconjugation.Organic & biomolecular chemistry · 2019Article
- Playing with the Molecules of Life.ACS chemical biology · 2018Review
- Development of optimized conditions for Glaser-Hay bioconjugations.Bioorganic chemistry · 2018Article
- Utilization of alkyne bioconjugations to modulate protein function.Bioorganic & medicinal chemistry letters · 2017Article
- Synthesis and incorporation of a caged tyrosine amino acid possessing a bioorthogonal handle.Tetrahedron letters · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The importance of bioconjugates within the field of chemistry drives the need for novel methodologies for their preparation. Well-defined and stable bioconjugates are easily accessible via the utilization of unnatural amino acids (UAAs). As such, we have synthesized and incorporated two new UAAs into green fluorescent protein, and optimized a novel Cadiot-Chodkiewicz bioconjugation, effectively expanding the toolbox of chemical reactions that can be employed in the preparation of bioconjugates.
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Registered trials
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