ArticleJournal of gastroenterology2016
Esophageal motility after peroral endoscopic myotomy for achalasia.
Article in Journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 20 citations in OpenAlex.
- High-Resolution Manometry in Treated Achalasia: Scoping Review and Novel Nomenclature.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026Article
- Article
- Clinical and functional outcome following robotic Heller-myotomy with partial fundoplication in patients with achalasia.Journal of robotic surgery · 2023Article
- Morphologic Changes in Esophageal Body Movement During Bolus Transport After Peroral Endoscopic Myotomy in Type III Achalasia.Journal of neurogastroenterology and motility · 2022Article
- Esophageal Motility Patterns After Peroral Endoscopic Myotomy in Patients With Achalasia.Journal of neurogastroenterology and motility · 2021Article
- Long-term outcomes of per-oral endoscopic myotomy compared to laparoscopic Heller myotomy for achalasia: a single-center experience.Surgical endoscopy · 2021Article
- Determining the Safety and Effectiveness of Electrocautery Enhanced Scissors for Peroral Endoscopic Myotomy (with Video).Clinical endoscopy · 2020Article
- Morphologic Restoration After Peroral Endoscopic Myotomy in Sigmoid-type Achalasia.Journal of neurogastroenterology and motility · 2020Article
- Achalasia: treatment, current status and future advances.The Korean journal of internal medicine · 2019Review
- Long-Term Efficacy of Peroral Endoscopic Myotomy for Patients with Achalasia: Outcomes with a Median Follow-Up of 36 Months.Digestive diseases and sciences · 2019Article
- Impact of esophageal flexion level on the surgical outcome in patients with sigmoid esophageal achalasia.Surgery today · 2017Article
- Per-oral endoscopic myotomy for achalasia cardia: outcomes in over 400 consecutive patients.Endoscopy international open · 2017Article
- Functional restoration of the esophagus after peroral endoscopic myotomy for achalasia.PloS one · 2017Article
- Long-term outcome of myotomy and fundoplication based on intraoperative real-time high-resolution manometry in achalasia patients.Annals of gastroenterologyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeroral endoscopic myotomy (POEM) has been introduced as a novel endoscopic treatment for achalasia. The aim of this work is to assess the changes in esophageal motility caused by POEM in patients with achalasia.
methodsForty-one patients with achalasia underwent POEM from September 2012 to November 2014. Esophageal motility of all patients was evaluated preoperatively and 1 month after POEM utilizing high-resolution manometry, which was performed with ten water swallows, ten steamed bread swallows, and multiple rapid swallows (MRS).
resultsIn single swallows, including liquid swallows and bread swallows, all the parameters of lower esophagus sphincter resting pressure (LESP), 4-s integrated relaxation pressure (4sIRP), and intra-bolus pressure (IBP) were decreased between pre- and post-POEM patients (all p < 0.05). Postoperatively, the trend of distal contractile integral (DCI) and distal esophageal peristaltic amplitude declined in subtype II and subtype III (subtype II: p < 0.05; subtype III: p > 0.05), but increased in subtype I (subtype I: p > 0.05). In liquid swallows, the Eckardt score of subtype II patients decreased with DCI, and distal esophageal peristaltic amplitude after POEM was significantly lower compared with those showing increased values of those two parameters (p < 0.05). In MRS, the rate of LES relaxation increased from 66.67 to 95.24%, but without normal response in all achalasia patients.
conclusionsPOEM reduces LES pressure in achalasia, and partly restores esophageal motility. POEM displayed varying effect on esophageal motility in patients with different patterns of swallowing. In addition, the changes in parameters associated with esophageal peristalsis correlated with decreases in Eckardt score.
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